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Transcriptional analysis of PPARgamma activation in control and PPARgamma null macrophages [ChIP-seq]
Transcriptional analysis of PPARgamma activation in control and PPARgamma null macrophages [GRO-seq]
Transcriptional analysis of PPARgamma activation in control and PPARgamma null macrophages [RNA-seq]
We profiled PPARg dependent gene expression changes during differntiation of 3T3L1 cell using PPARg siRNA 3T3-L1 (Pre-adipocyte) cell line was induced to differentiate using standard adipocyte differentiation media (IBMX, Dex and Insulin) 48hrs post-confluency. RNA was harvested at day -2 (confluent...
ORGANISM(S): Mus musculus 
PPARγ is a member of the nuclear receptor family for which agonist ligands have anti-growth effects. However, clinical studies using PPARγ ligands as a monotherapy failed to show a beneficial effect. Here we have studied the effects of PPARγ activation with chemotherapeutic agents in current us...
ORGANISM(S): Homo sapiens 
The nuclear receptor Peroxisome Proliferator Activated Receptor gamma (PPARgamma) is known to regulate lipid metabolism in many tissues, including macrophages. Here we report that macrophage respiration is enhanced by rosiglitazone, an activating PPARgamma ligand, in a PPARgamma dependent manner. Mo...
ORGANISM(S): Mus musculus 
2018-09-06 | GSE111104 | GEO
The nuclear receptor Peroxisome Proliferator Activated Receptor gamma (PPARgamma) is known to regulate lipid metabolism in many tissues, including macrophages. Here we report that macrophage respiration is enhanced by rosiglitazone, an activating PPARgamma ligand, in a PPARgamma dependent manner. Mo...
ORGANISM(S): Mus musculus 
2018-09-06 | GSE111102 | GEO
The nuclear receptor Peroxisome Proliferator Activated Receptor gamma (PPARgamma) is known to regulate lipid metabolism in many tissues, including macrophages. Here we report that macrophage respiration is enhanced by rosiglitazone, an activating PPARgamma ligand, in a PPARgamma dependent manner. Mo...
ORGANISM(S): Mus musculus 
2018-09-06 | GSE111103 | GEO
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