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Background: Previous expression quantitative trait loci (eQTL) studies have identified thousands of genetic variants to be associated with gene expression at the mRNA level in the human liver. However, protein expression often correlates poorly with mRNA levels. Thus, protein quantitative trait loci...
ORGANISM(S): Homo sapiens (Human) 
2020-07-21 | PXD019169 | Pride
CSF pQTL study in the Japanese population
Proteogenomics studies generate hypotheses on protein function and provide genetic evidence for drug target prioritization. Most previous work has been conducted using affinity-based proteomics approaches. These technological face challenges, such as uncertainty regarding target identity, non-specif...
ORGANISM(S): Homo sapiens (Human) 
2023-12-19 | PXD042852 | Pride
Cerebrospinal fluid (CSF) is virtually the only one accessible source of proteins derived from the central nervous system (CNS) of living humans and possibly reflects the pathophysiology of a variety of neuropsychiatric diseases. However, little is known regarding the genetic basis of variation in p...
ORGANISM(S): Homo sapiens 
2016-12-30 | GSE83710 | GEO
Cerebrospinal fluid (CSF) is virtually the only one accessible source of proteins derived from the central nervous system (CNS) of living humans and possibly reflects the pathophysiology of a variety of neuropsychiatric diseases. However, little is known regarding the genetic basis of variation in p...
ORGANISM(S): Homo sapiens 
2016-12-30 | GSE83709 | GEO
Cerebrospinal fluid (CSF) is virtually the only one accessible source of proteins derived from the central nervous system (CNS) of living humans and possibly reflects the pathophysiology of a variety of neuropsychiatric diseases. However, little is known regarding the genetic basis of variation in p...
ORGANISM(S): Homo sapiens 
2016-12-30 | GSE83708 | GEO
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