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TranscriptomicsUlipristal and Progesterone Receptor
This SuperSeries is composed of the following subset Series: GSE37353: Gene expression profiling of ovaries collected from mice treated with or without Ulipristal GSE37354: Gene expression profiling of ovaries collected from wild type (WT) mice and progesterone receptor (PR) knock out mice Refer to ...
ORGANISM(S): Mus musculus 
2012-10-04 | E-GEOD-37383 | biostudies-arrayexpress
TranscriptomicsIdentification of Murine Uterine Genes Regulated in a Ligand-Dependent Manner by the Progesterone Receptor.
Progesterone (P4) acting through its cognate receptor, the progesterone receptor (PR), plays an important role in uterine physiology. The PR knockout (PRKO) mouse has demonstrated the importance of the P4-PR axis in the regulation of uterine function. To define the molecular pathways regulated by P4...
ORGANISM(S): Mus musculus 
2012-08-06 | E-GEOD-39920 | biostudies-arrayexpress
TranscriptomicsMicroRNA signatures predict Estrogen receptor, Progesterone receptor and HER2/neu receptor status in Breast Cancer
Breast cancer is a heterogeneous disease encompassing a number of phenotypically diverse tumours. Expression levels of the estrogen, progesterone and HER2/neu receptors which characterise clinically distinct breast tumors have been shown to change during disease progression and in response to system...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-15885 | biostudies-arrayexpress
TranscriptomicsGenome-wide Profiling of Progesterone Receptor and GATA2 Binding in the Mouse Uterus [Affymetrix]
Progesterone (P4) signaling through its nuclear transcription factor, the progesterone receptor (PR), is essential for normal uterine function. Although deregulation of PR mediated signaling is known to underscore uterine dysfunction and a number of endometrial pathologies, the early molecular mech...
ORGANISM(S): Mus musculus 
2012-09-06 | E-GEOD-34902 | biostudies-arrayexpress
GenomicsGenome-wide Profiling of Progesterone Receptor and GATA2 Binding in the Mouse Uterus [ChIP-Seq]
Progesterone (P4) signaling through its nuclear transcription factor, the progesterone receptor (PR), is essential for normal uterine function. Although deregulation of PR mediated signaling is known to underscore uterine dysfunction and a number of endometrial pathologies, the early molecular mech...
ORGANISM(S): Mus musculus 
2012-09-06 | E-GEOD-34927 | biostudies-arrayexpress
TranscriptomicsPhysiological Vascular Permeability Requires Induction of Endothelial NR4A1 by Progesterone Receptor [RNA-Seq]
Vascular permeability is frequently associated with inflammation and it is triggered by chemokines and by a cohort of secreted permeability factors, such as VEGF. In contrast, here we showed that the physiological vascular permeability that precedes implantation is directly controlled by progestero...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-43788 | biostudies-arrayexpress
GenomicsPhysiological Vascular Permeability Requires Induction of Endothelial NR4A1 by Progesterone Receptor [ChIP-Seq]
Vascular permeability is frequently associated with inflammation and it is triggered by chemokines and by a cohort of secreted permeability factors, such as VEGF. In contrast, here we showed that the physiological vascular permeability that precedes implantation is directly controlled by progestero...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-43786 | biostudies-arrayexpress
TranscriptomicsSelective suppression of endothelial cytokine production by progesterone receptor [RNA-seq]
Steroid hormones are well-recognized suppressors of the inflammatory response, however, their cell- and tissue-specific effects in the regulation of inflammation are far less understood, particularly for the sex-related steroids. To determine the contribution of progesterone in the endothelium, we h...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-46502 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of MDA-MB-231 mammary cancer cells conditionally expressing progesterone receptor isoforms PRA and PRB
The progesterone receptor isoforms PRA and PRB are implicated in breast cancer development and metastasis. Expression ratio PRA/PRB is imbalanced in such cancers under the influence of MAPK-dependent extracellular stimuli that strongly impact progesterone-responsiveM- transcriptional regulation. In...
ORGANISM(S): Homo sapiens 
2012-06-11 | E-TABM-1215 | biostudies-arrayexpress
GenomicsGenome-wide Profiling of Progesterone Receptor and GATA2 Binding in the Mouse Uterus
This SuperSeries is composed of the following subset Series: GSE34902: Genome-wide Profiling of Progesterone Receptor and GATA2 Binding in the Mouse Uterus [Affymetrix] GSE34927: Genome-wide Profiling of Progesterone Receptor and GATA2 Binding in the Mouse Uterus [ChIP-Seq] Refer to individual Serie...
ORGANISM(S): Mus musculus 
2012-09-06 | E-GEOD-40663 | biostudies-arrayexpress
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