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TranscriptomicsTranscription profiling of rat heart tissue from animals aged 4 and 22 months
Myocardial aging leads to a reduction of beta-adrenergic receptor-induced metabolic and contractile responsiveness. We hypothesize that a change in the patterns of gene expression is important in these age-related events. To test this, hearts were harvested from young and aged male rats (3-4 and 20-...
ORGANISM(S): Rattus norvegicus 
2007-10-10 | E-GEOD-421 | biostudies-arrayexpress
UnknownACKR3 Proximity Labeling Identifies Novel G protein- and β-arrestin-independent GPCR Interacting Proteins.
Not available
S-EPMC10896341 | biostudies-literature
UnknownAged G Protein-Coupled Receptor Kinase 3 (Grk3)-Deficient Mice Exhibit Enhanced Osteoclastogenesis and Develop Bone Lesions Analogous to Human Paget's Disease of Bone.
Not available
S-EPMC10093054 | biostudies-literature
MetabolomicsDeep longitudinal multi-omics analysis of Bordetella pertussis cultivated in bioreactors highlights medium starvations and transitory metabolisms, associated to vaccine antigen biosynthesis variations and global virulence regulation

Bordetella pertussis is the bacterial causative agent of whooping cough, a serious respiratory illness. An extensive knowledge on its virulence regulation and metabolism is a key factor to ensure pertussis vaccine manufacturing process robustness. The aim of this study was to refine our ...

2023-02-21 | MTBLS5762 | MetaboLights
UnknownThe glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout.
Not available
S-EPMC6407216 | biostudies-literature
UnknownNeuronal activation of Gαq EGL-30/GNAQ late in life rejuvenates cognition across species.
Not available
S-EPMC10627507 | biostudies-literature
UnknownMultiple kinesin motors coordinate cytoplasmic RNA transport on a subpopulation of microtubules in Xenopus oocytes.
Not available
S-EPMC2581415 | biostudies-literature
UnknownEarly Relapse in First-Line Follicular Lymphoma: A Review of the Clinical Implications and Available Mitigation and Management Strategies.
Not available
S-EPMC8594248 | biostudies-literature
Unknown3-Bromopyruvate inhibits pancreatic tumor growth by stalling glycolysis, and dismantling mitochondria in a syngeneic mouse model
Not available
S-EPMC9729896 | biostudies-literature
UnknownThe humanized DRAGA mouse (HLA-A2. HLA-DR4. RAG1 KO. IL-2R g c KO. NOD) establishes inducible and transmissible models for influenza type A infections.
Not available
S-EPMC7553695 | biostudies-literature
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