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The chromatin regulator Aiolos and the transcriptional coactivator OBF-1 have been implicated in regulating aspects of B cell maturation and activation. Mice lacking either of these factors have a largely normal early B cell development. However, when both factors are eliminated simultaneously a blo...
ORGANISM(S): Mus musculus 
scRNA-Seq to study the impact of HIV-1 on pre-DC biology [PreDC_Single_Cell_Exp1]
Melanoma cell lines: generated from pre vs generated post anti-PD-1 therapy
Exercise Training Modulates the Hepatic Pre-Metastatic Niche by Regulating TREM-1 Signaling
Myotonic dystrophy type 1 (DM1), the most common muscular dystrophy in adults, is caused by the expression of expanded CUG repeats, which sequester the MBNL1 RNA binding protein. Cardiac involvement, which is characterized by conduction defects and arrhythmias, is the second cause of death of DM1 pa...
ORGANISM(S): Homo sapiens 
Pancreata from nPOD registered donors with stage 1 pre-symtomatic type 1 diabetes (T1D) with auto-antibodies were dissected by laser microdissection (LMD) and the proteome profiles were compared to age/sex matched controls.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-08-25 | MSV000090212 | MassIVE
LINE-1 retrotransposition impacts the genome of human pre-implantation embryos and extraembryonic tissues [hEMB]
Urease pre-treatment of urine has been utilized since the early 1960s to remove high levels of urea from samples prior to further processing and analysis by gas chromatography–mass spectrometry (GC–MS). Aside from the obvious depletion or elimination of urea, the effect, if any, of urease pre-treatm...
2014-05-21 | MTBLS71 | MetaboLights
Abnormal neutrophil signature in the blood and pancreas of pre-symptomatic and symptomatic type 1 diabetes
Pre-DC have been initially described through their ontogeny. Our lab reported for the first time a pre-DC functional specificity in the context of HV-1 capture, infection and in vitro transmission as a consequence of their constitutive expression of Siglec-1. However, pre-DC immune response to viral...
ORGANISM(S): Homo sapiens 
2023-01-13 | GSE201327 | GEO
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