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Mandibular and Femur-Derived Ligated preosteoclasts from LSD1WT and cKO mice
Expression data from CD115+ preosteoclasts stimulated by conditioned medium from CT-26 cells
It is unclear that osteoclast lineages can sense mechanical stimuli, mainly by lack of information about the presence or absence of mechano-sensing organelles in these cells. Primary cilium is a microtubule-based organelle, which can translate mechanical loading signals into biochemical and transcri...
ORGANISM(S): Mus musculus 
2024-02-02 | GSE246066 | GEO
We investigated the skeletal effects of conditional overexpression of Runx1 in preosteoclasts by crossing novel Runx1 gain-of-function mice (Rosa26-LSL-Runx1) with LysM-Cre transgenic mice.
ORGANISM(S): Mus musculus 
2022-10-24 | GSE216312 | GEO
Bone remodeling is orchestrated by the balanced activity of bone-resorbing osteoclasts and bone-forming osteoblasts. Interferon regulatory factor 5 (IRF5), a member of the IRF family of transcription factors, serves as a critical regulator of macrophage immune-related activity. However, macrophages ...
ORGANISM(S): Mus musculus 
2026-07-29 | GSE297530 | GEO
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