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MetabolomicsOn-line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process
The real-time monitoring of metabolites (RTMet) is instrumental for the industrial production of biobased fermentation products. This study shows the first application of untargeted on-line metabolomics for the monitoring of undiluted fermentation broth samples taken automatically from a 5 L bioreac...
2023-04-26 | MTBLS5197 | MetaboLights
TranscriptomicsTranscription profiling of Neisseria meningitidis knock out mutant of snC transcriptional regulator compared to parent strains
Knock out mutant of asnC transcriptional regulator (NMB0573) in N. meningitidis MC58 compared to parent strains (capsule deletion mutant) grown in normal bacterial solid media plate conditions.
ORGANISM(S): Neisseria meningitidis 
2007-04-05 | E-MEXP-925 | biostudies-arrayexpress
UnknownMetabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells.
Not available
S-EPMC5193007 | biostudies-literature
MetabolomicsStreamlined identification of strain engineering targets for bioprocess improvement using metabolic pathway enrichment analysis
Metabolomics is a powerful tool for the identification of genetic targets for bioprocess optimisation. However, in most cases, only the biosynthetic pathway directed to product formation is analysed, limiting the identification of these targets. Some studies have used untargeted metabolomics, allowi...
2023-08-31 | MTBLS6667 | MetaboLights
ProteomicsBurger_et_al_ilicicolin_metabolomics
In this study, the ilicicolin biosynthetic gene cluster (BGC) in Trichoderma reesei was genetically activated, and a series of gene cluster enzyme deletions were performed. Mycelia were harvested and subjected to polar extraction. The resulting polar extracts were analyzed using an untargeted lipido...
ORGANISM(S): Trichoderma Reesei (ncbitaxon:51453) 
MSV000095813 | MassIVE
UnknownPredictive value and clinical utility of centrally assessed ER, PgR, and Ki-67 to select adjuvant endocrine therapy for premenopausal women with hormone receptor-positive, HER2-negative early breast cancer: TEXT and SOFT trials.
Not available
S-EPMC4749471 | biostudies-literature
TranscriptomicsEffects of a diet high in monounsaturated fat and a full Mediterranean diet on PBMC whole genome gene expression and plasma proteins
This study aimed to identify the effects of replacement of saturated fat (SFA) by monunsaturated fat (MUFA) in a western-type diet and the effects of a full Mediterranean (MED) diet on whole genome PBMC gene expression and plasma protein profiles. Abdominally overweight subjects were randomized to a...
ORGANISM(S): Homo sapiens 
2012-08-02 | E-GEOD-30509 | biostudies-arrayexpress
UnknownImpact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trial.
Not available
S-EPMC5101790 | biostudies-literature
UnknownAntibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth.
Not available
S-EPMC8426205 | biostudies-literature
UnknownTailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
Not available
S-EPMC6193457 | biostudies-literature
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