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TranscriptomicsGene expression analysis of Cbp deficient LSK cells
The transcriptional coactivator Cbp is critical for hematopoietic stem cell (HSC) development. However, its role in adult HSC and the mechanistic detail of Cbp control of HSC function remains unknown. Using conditional deletion of Cbp in the adult HSC compartment, we demonstrate an altered balance b...
ORGANISM(S): Mus musculus 
2011-12-15 | E-GEOD-25268 | biostudies-arrayexpress
GenomicsGenome-wide analysis of the binding pattern of the transcriptional co-activator Cbp.
The transcriptional coactivator Cbp is critical for hematopoietic stem cell (HSC) development. However, its role in adult HSC and the mechanistic detail of Cbp control of HSC function remain unknown. Using conditional deletion of Cbp in the adult HSC compartment, we demonstrate an altered balance be...
ORGANISM(S): Mus musculus 
2011-12-15 | E-GEOD-25265 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-sequencing of epithelial cells, endothelial cells and macrophages from mouse submandibular salivary glands
The salivary glands often become damaged in individuals receiving radiotherapy for head and neck cancer, resulting in chronic dry mouth. This leads to detrimental effects on their health and quality of life, for which there is no regenerative therapy. Macrophages are the predominant immune cell in t...
ORGANISM(S): Mus musculus 
2023-10-01 | E-MTAB-13374 | biostudies-arrayexpress
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