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MetabolomicsPlasma metabolomic and lipidomic signatures characteristic of treatment non-response in rheumatoid arthritis

Objectives: This study aimed to investigate plasma metabolomic and lipidomic profiles in rheumatoid arthritis (RA) to identify potential biomarkers for distinguishing treatment responses.

Methods: Plasma samples...

2026-06-02 | MTBLS13243 | MetaboLights
MetabolomicsPlasma metabolomic and lipidomic signatures characteristic of treatment non-response in rheumatoid arthritis

Objectives: This study aimed to investigate plasma metabolomic and lipidomic profiles in rheumatoid arthritis (RA) to identify potential biomarkers for distinguishing treatment responses.

Methods: Plasma samples w...

2026-06-02 | MTBLS13238 | MetaboLights
MetabolomicsUntargeted and Targeted Plasma Metabolomics Analysis Identifies Aberrant Amino Acid Metabolism in Early Primary Angle-Closure Glaucoma

Purpose: To explore the plasma metabolite profiles of patients with early primary angle-closure glaucoma (PACG) and investigate their relevance to ocular characteristics and retinal-associated parameters.

Methods：Plasma samples were obtained from 30 early PACG patients and 30 healthy contro...

2026-01-06 | MTBLS13608 | MetaboLights
TranscriptomicsCanonical and non-canonical EcfG sigma factors control the general stress response in Rhizobium etli
A core component of the M-NM-1-proteobacterial general stress response is the extracytoplasmic function (ECF) sigma factor EcfG, exclusively present in this taxonomic class. Half of the completed M-NM-1-proteobacterial genome sequences contain two or more copies of genes encoding M-OM-^CEcfG-like si...
ORGANISM(S): Rhizobium etli CFN 42 
2013-12-20 | E-GEOD-53517 | biostudies-arrayexpress
UnknownReasons for non-adherence to cardiometabolic medications, and acceptability of an interactive voice response intervention in patients with hypertension and type 2 diabetes in primary care: a qualitative study.
Not available
S-EPMC5724082 | biostudies-literature
TranscriptomicsLong non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes
Investigating the response of long non-coding RNA expression to LPS stimulation in human monocytes. This experiment is related to the microarray study E-MTAB-2408.
ORGANISM(S): Homo sapiens 
2014-04-25 | E-MTAB-2399 | biostudies-arrayexpress
TranscriptomicsExploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity (miRNA)
The well-defined battery of in vitro systems applied within chemical cancer risk assessment is often characterised by a high false-positive rate, thus repeatedly failing to correctly predict the in vivo genotoxic and carcinogenic properties of test compounds. Toxicogenomics, i.e. mRNA-profiling, has...
ORGANISM(S): Mus musculus 
2016-06-28 | E-GEOD-72014 | biostudies-arrayexpress
TranscriptomicsPromiscuous targeting of bromodomains by Bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia [set2]
Bromodomains (BRDs) have emerged as compelling targets for cancer therapy. The development of selective and potent BET inhibitors and their significant activity in diverse tumor models has rapidly translated into clinical studies and has motivated drug development efforts targeting non-BET BRDs. How...
ORGANISM(S): Homo sapiens 
2016-10-25 | E-GEOD-78829 | biostudies-arrayexpress
TranscriptomicsPromiscuous targeting of bromodomains by Bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia [set 1]
Bromodomains (BRDs) have emerged as compelling targets for cancer therapy. The development of selective and potent BET inhibitors and their significant activity in diverse tumor models has rapidly translated into clinical studies and has motivated drug development efforts targeting non-BET BRDs. How...
ORGANISM(S): Homo sapiens 
2016-10-25 | E-GEOD-78827 | biostudies-arrayexpress
ProteomicsUrine proteomics in primary antiphospholipid syndrome
In this study, using proteomics study of urine samples from patients with primary APS (PAPS) and healthy controls (HC), we identified several proteins that discriminated Obstetric APS (OAPS) and Thrombotic APS (TAPS) from each other, as well as from HC.
ORGANISM(S): Homo Sapiens 
2021-08-04 | PXD027694 |
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