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GenomicsG6PD Viangchan Prime Editing
Correction of G6PD Viangchan mutation using prime editing strategy
PRJEB83012 | ENA
GenomicsPrime editing for functional repair in patient-derived disease models
Prime editing is a novel genome editing technology using fusion proteins of Cas9-nickase and reverse transcriptase, that holds promise to correct a wide variety of genetic defects. We succeeded in efficient prime editing and functional recovery of disease-causing mutations in patient-derived liver a...
EGAS00001004611 | EGA
GenomicsEvaluating CRISPR-based Prime Editing for cancer modeling and CFTR repair in organoids
We evaluate CRISPR-based prime editing for application in organoids. First we model mutations in TP53 in intestinal and hepatocyte oganoids and determine the efficiency and accuracy of mutation induction on multiple targets. Then, to evaluate potential clinical applicability of prime editing we repa...
EGAS00001005358 | EGA
GenomicsImproving prime editing with an endogenous small RNA-binding protein
Improving prime editing with an endogenous small RNA-binding protein
PRJNA1073019 | ENA
GenomicsChromatin context-dependent regulation and modulation of prime editing [amplicon]
Chromatin context-dependent regulation and modulation of prime editing [amplicon]
PRJNA949970 | ENA
GenomicsMutation-specific reporter for optimization and enrichment of prime editing
Mutation-specific reporter for optimization and enrichment of prime editing
PRJNA802825 | ENA
GenomicsLDLR variant classification through activity-normalized prime editing screening
LDLR variant classification through activity-normalized prime editing screening
PRJNA1457355 | ENA
GenomicsImproving prime editing with an endogenous small RNA-binding protein
Improving prime editing with an endogenous small RNA-binding protein
PRJNA1065772 | ENA
UnknownCircular RNA-mediated inverse prime editing in human cells.
Not available
S-EPMC12125189 | biostudies-literature
GenomicsChromatin context-dependent regulation and modulation of prime editing [RNA-seq]
Chromatin context-dependent regulation and modulation of prime editing [RNA-seq]
PRJNA949972 | ENA
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