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TranscriptomicsRNA-seq in Raji cells with inducible BZLF1 prior to and after induction of EBV's lytic cycle by doxycycline
(i) RNA transcripts of Raji iBZLF1 cells (https://www.biorxiv.org/content/10.1101/573659v1) were compared between non-induced cells and cells induced with doxycycline (100 ng/ ml) for 6 h. Human (Hg19) as well as viral (EBV, Raji KF717093.1) transcripts were analyzed. Artificial ERCC Spike-ins (Ther...
ORGANISM(S): Homo sapiens 
2019-01-01 | E-MTAB-7820 | biostudies-arrayexpress
TranscriptomicsCapture-C identification of chromatin interactions of 53 selected cellular loci prior to and post induction of EBV's lytic cycle in Raji cells
Identification of specific chromatin interactions of 53 selected genes with the Capture-C technique in Raji iBZLF1 cells prior to and 6 or 15 h after induction of EBV’s lytic cycle. The experiments were performed as triplicates.
ORGANISM(S): Homo sapiens 
2019-04-05 | E-MTAB-7825 | biostudies-arrayexpress
TranscriptomicsATAC-seq analyses with results from DG75 cells prior to and post induction of two versions of BZLF1.
The aim of the experiment was to identify accessible (open) chromatin regions in the genome prior to and post induction of EBV's BZLF1 protein. Two versions of BZLF1 were employed: full-length and activation-domain (AD)-truncated BZLF1 non-induced and induced for 15 h. The experiments were performed...
ORGANISM(S): Homo sapiens 
2021-02-07 | E-MTAB-8420 | biostudies-arrayexpress
TranscriptomicsRNA-seq data from DG75 cells with inducible BZLF1 prior to and after induction of EBV's lytic cycle by doxycycline.
(i) Transcripts of DG75 iBZLF1 cells were analyzed comparing non-induced cells and cells induced with doxycycline (100 ng/ ml) for 6 h. Doxycycline induces the expression of the full length viral transcription factor BZLF1. (ii) For control purposes, the transcripts of DG75 cells equipped with a dox...
ORGANISM(S): Homo sapiens 
2021-02-07 | E-MTAB-8426 | biostudies-arrayexpress
TranscriptomicsIdentification of chromatin interactions of 49 selected cellular loci prior to and post induction of BZFL1 in DG75 cells using the Capture-C technology.
Identification of specific chromatin interactions of 49 selected genes with the Capture-C technique in DG75 iBZLF1 cells prior to and 15 h after expression of EBV's protein BZLF1. The experiments were performed as triplicates.
ORGANISM(S): Homo sapiens 
2021-02-07 | E-MTAB-8427 | biostudies-arrayexpress
TranscriptomicsDefining a No Observable Transcriptional Effect Level (NOTEL) for low dose N-OH-PhIP exposures in human BEAS-2B bronchioepithelial cells
The estimation of acceptable exposure levels for genotoxicants is accomplished by defining thresholds from apical endpoints, or by modeling points of departure from data that are acquired from high dose experiments, followed by linear extrapolation of the response through zero. We recently proposed ...
ORGANISM(S): Homo sapiens 
2011-12-22 | E-GEOD-34635 | biostudies-arrayexpress
ProteomicsA comprehensive view on r- protein binding and rRNA domain structuring during early ribosome formation
Formation of the eukaryotic ribosomal subunits follows a strict regime to assemble ribosomal proteins (r-protein) with ribosomal RNAs (rRNA) while removing internal (ITS) and external (ETS) transcribed rRNA spacers. During early stages of large subunit (LSU) formation, ITS2 together with six assembl...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-02-02 | PXD058994 | Pride
Ribosome biogenesis Single particle cryo-em Lsu assembly Ssu processome Rrna domain folding Ribosomal protein assembly 
UnknownA Pitfall in Heavy Metal Separation with Amino-modified Silica Adsorbents from Aqueous Solution: The Occurring pH Shift.
Not available
S-EPMC9059311 | biostudies-literature
TranscriptomicsExpression data from breast cancer tumor-initiating cells
We have generated tumorigenic (S2N) and non-tumorigenic (S2), normal-like to basal-like breast cancer cell lines from primary tumors. At high in vivo inoculation cell numbers of 10^6 cells/mouse both S2N and S2 monolayer as well as sphere culture cells grew at similar rates. However, at low inoculat...
ORGANISM(S): Homo sapiens 
2012-12-21 | E-GEOD-32526 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression analysis in motor and sensory cortex as a result of experimental autoimmune encephalomyelitis (EAE), a neuroinflammatory model for Multiple sclerosis.
We performed micrarrays to investigate neuronal gene expression changes during acute inflammatory CNS axon injury using the murine myelin oligodendrocyte glycoprotein 35-55 (MOG35-55)-induced experimental autoimmune encephalomyelitis (EAE) model. The present study was assigned to assess the direct a...
ORGANISM(S): Mus musculus 
2014-10-01 | E-GEOD-47900 | biostudies-arrayexpress
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