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TranscriptomicsDysregulation of pathways involved in the processing of cancer and microenvironment information in MCA+TPA transformed C3H/10T1/2 cells
The two-stage cell transformation assay is an in vitro model cell culture system to identify the ability of chemicals to act as initiators or promoters of cell transforma- tion and also to study the cellular and molecular mechanisms of chemically induced morphological and neoplastic cell transformat...
ORGANISM(S): Mus musculus 
2013-04-26 | E-GEOD-41142 | biostudies-arrayexpress
TranscriptomicsDiethyl maleate inhibits MCA+TPA transformed cell growth via modulation of GSH, MAPK, and cancer pathways
Murine or human cancer cells have high glutathione levels. Depletion of the elevated GSH inhibits proliferation of cancer cells. Molecular basis for this observation is little understood. In an attempt to find out the underlying mechanism, we reproduced these effects in transformed C3H10T1/2 and BAL...
ORGANISM(S): Mus musculus 
2014-06-02 | E-GEOD-44650 | biostudies-arrayexpress
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