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MetabolomicsMetabolomics analysis reveals the participation of efflux pumps and ornithine in the response of Pseudomonas putida DOT-T1E cells to challenge with propranolol
Efflux pumps are critically important membrane components that play a crucial role in strain tolerance in Pseudomonas putida to antibiotics and aromatic hydrocarbons that result in these toxicants being expelled from the bacteria. Here, the effect of propranolol on P. putida was examined by sudden a...
2016-08-23 | MTBLS320 | MetaboLights
TranscriptomicsPropranolol inhibition of melanoma growth
We investigated the effect of a daily propranolol treatment (0.5mg/mL in the water bottle) on human melanoma xenografts development and the subsequent transcriptomic variations
ORGANISM(S): Homo sapiens 
2014-05-30 | E-MTAB-2404 | biostudies-arrayexpress
TranscriptomicsPropranolol inhibition of melanoma growth
We investigated the effect of a daily propranolol treatment (0.5mg/mL in the water bottle) on human melanoma xenografts development and the subsequent transcriptomic variations
ORGANISM(S): Homo sapiens 
2014-05-30 | E-MTAB-2405 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of the effects of propranolol on angiosarcoma tumor cells
Analysis of the effects of 4 hr and 24 hr propranolol treatment on gene expression of SVR mouse angiosarcoma cells. The hypothesis tested in the present study was that inhibiton of beta adrenergic receptor signaling could ablate the oncogenic properties of angiosarcoma cells. Results provide importa...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-42534 | biostudies-arrayexpress
TranscriptomicsMicroRNA Expression in Rat Myocardial Infarction intervened by propranolol
We established a rat model of myocardial Infarction by performing a surgical operation of left anterior descending coronary artery occlusion under sterie conditions. Wistar rats were previously randomly divided into 4 groups: control, ischemia, ischemia-propranolol, and non-ischemia-propranolol. Our...
ORGANISM(S): Rattus norvegicus 
2010-06-19 | E-GEOD-18129 | biostudies-arrayexpress
ProteomicsCritical role of Aquaporin-1 and telocytes in infantile hemangioma response to propranolol beta-blockade
Propranolol, a non-selective β-adrenergic receptor (ADRB) antagonist, is the first-line therapy for severe infantile hemangiomas (IH). Since the incidental discovery of propranolol efficacy in IH, preclinical and clinical investigations have shown evidence of adjuvant propranolol response in some ma...
ORGANISM(S): Homo sapiens (Human) 
2021-01-25 | PXD021457 | Pride
Hemangioma  propranolol  telocyte  aquaporin-1  angiogenesis. 
GenomicsPropranolol inhibit tumor growth through reducing T cell exhaustion
Propranolol inhibit tumor growth through reducing T cell exhaustion
PRJNA862514 | ENA
GenomicsPropranolol exhibits activity against hemangiomas independent of beta blockade
Propranolol exhibits activity against hemangiomas independent of beta blockade
PRJNA575740 | ENA
TranscriptomicsEffect of propranolol on differential gene expression in peripheral blood monocytes from mice subject to repeated social defeat
This study tested the effects of repeated social defeat (RSD) on gene expression in peripheral blood monocytes and examined the extent to which these effects were abrogated by the beta-adrenergic antagonist propranolol. Study Type: Risk prediction Gene expression profiling was carried out on periphe...
ORGANISM(S): Mus musculus 
2013-11-04 | E-GEOD-47153 | biostudies-arrayexpress
TranscriptomicsPropranolol inhibit tumor growth through reducing T cell exhaustion
Recently, targeting or reinvigorating exhausted T cells have become the focus of cancer immunotherapy. Propranolol, a non-selection β1 and β2 adrenergic receptor blocker, or in combination with other drug, can inhibit the development of various tumors. Additionally, β2-adrenergic receptor (ADRB2) si...
ORGANISM(S): Mus musculus 
2023-04-28 | GSE209807 | GEO
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