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ModelsProctor2010 - UCHL1 Protein Aggregation
This a model from the article: Modelling the Role of UCH-L1 on Protein Aggregation in Age-Related Neurodegeneration. Proctor CJ, Tangeman PJ, Ardley HC. PLoS One. 2010 Oct 6;5(10):e13175 20949132 , A...
2024-09-02 | BIOMD0000000293 | BioModels
ModelsAuer2010 - Correlation between lag time and aggregation rate in protein aggregation
Auer2010 - Correlation between lag time and aggregation rate in protein aggregation This model is described in the article: Insight into the correlation between lag time and aggregation rate in the kinetics of protein aggregation. Auer S, Kashchiev D. Proteins 2010 Aug; 78(1...
2024-09-02 | BIOMD0000000555 | BioModels
ModelsVazquez2014 - Chemical inhibition from amyloid protein aggregation kinetics
Vazquez2014 - Chemical inhibition from amyloid protein aggregation kinetics This model is described in the article: Modeling of chemical inhibition from amyloid protein aggregation kinetics. Vázquez JA. BMC Pharmacol Toxicol 2014; 15(1): 9 Abstract: BACKGROUNDS: The p...
2024-09-02 | BIOMD0000000532 | BioModels
ModelsMorris2008 - Fitting protein aggregation data via F-W 2-step mechanism
Morris2008 - Fitting protein aggregation data via F-W 2-step mechanism This model is described in the article: Fitting neurological protein aggregation kinetic data via a 2-step, minimal/"Ockham's razor" model: the Finke-Watzky mechanism of nucleation followed by autocatalytic ...
2024-09-02 | BIOMD0000000567 | BioModels
Genomicstissue-specific protein aggregation in C. elegans
Tissue-specific transcriptome profiling of Protein Aggregation in Caenorhabditis elegans
PRJEB41493 | ENA
MetabolomicsUsing an NMR metabolomics approach to investigate the pathogenicity of amyloid-beta and alpha-synuclein
INTRODUCTION: The pathogenicity at differing points along the aggregation pathway of many fibril-forming proteins associated with neurodegenerative diseases is unclear. Understanding the effect of different aggregation states of these proteins on cellular processes is essential to enhance understand...
2018-06-11 | MTBLS455 | MetaboLights
UnknownAge-Dependent Protein Aggregation Initiates Amyloid-β Aggregation.
Not available
S-EPMC5434662 | biostudies-literature
GenomicsTargeting DNA topoisomerases or checkpoint kinases forces a shift in global protein homeostasis, triggering widespread protein aggregation
Targeting DNA topoisomerases or checkpoint kinases forces a shift in global protein homeostasis, triggering widespread protein aggregation
PRJNA727579 | ENA
ModelsProctor2011_ProteinHomeostasis_NormalCondition
This model is from the article: Modelling the Role of the Hsp70/Hsp90 System in the Maintenance of Protein Homeostasis Proctor CJ, Lorimer IAJ PLoS ONE2011; 6(7): e22038. doi:10.1371/journal.pone.0022038, Abstract: Neurodegeneration is a...
2024-09-02 | BIOMD0000000344 | BioModels
ProteomicsA proteome scale study reveals how plastic surfaces and agitation promote protein aggregation
Protein aggregation in biotherapeutics can reduce their activity and effectiveness. It may also promote immune reactions responsible for severe adverse effects. The impact of plastic materials on protein destabilization is not totally understood. Here, we propose to deconvolve the effects of materia...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-03-11 | PXD038266 | Pride
A proteome scale study reveals how plastic surfaces and agitation promote protein aggregation 
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