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Metabolomics1H NMR metabolomic and transcriptomic analyses reveal urinary metabolites as biomarker candidates in response to protein undernutrition in adult rats

BACKGROUND: Protein undernutrition is prevalent mainly among elderly people, and it could develop diseases such as sarcopenia. Urinary metabolites may become biomarkers reflecting protein undernutrition, but this has been insufficiently investigated.

OBJECTIVE:

2021-05-27 | MTBLS1452 | MetaboLights
ProteomicsKILchip v1.0: A novel Plasmodium falciparum merozoite protein microarray to facilitate malaria vaccine candidate prioritization7
Passive transfer studies in humans clearly demonstrated the protective role of IgG antibodies against malaria. Identifying the precise parasite antigens that mediate immunity is essential for vaccine design, but has proved difficult. Completion of the Plasmodium falciparum genome revealed thousands ...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2021-02-12 | PXD011724 | Pride
Plasmodium falciparum Protein microarray Merozoite Vaccine candidates Bioinformatics Antibodies 
GenomicsProtein microarray analysis of ACAP1 interacting proteins
Protein microarray analysis of ACAP1 interacting proteins
PRJNA1499661 | ENA
TranscriptomicsCLAMP Protein Binding Microarray (PBM) experiment
To investigate the DNA binding specificity of the CLAMP protein, we have designed a custom PBM to interrogate the binding of CLAMP to DNA sequences extracted from the Drosophila melanogaster genome. Specific regions were extracted based on ChIP-seq data, motif occurence and proximity to gene transcr...
ORGANISM(S): Drosophila melanogaster 
2016-07-17 | E-GEOD-83442 | biostudies-arrayexpress
ProteomicsKILchip v1.0 A novel Plasmodium falciparum merozoite protein microarray to facilitate malaria vaccine candidate prioritization
KILchip v1.0: a novel protein microarray to facilitate high throughput multiplexed antibody detection from individual samples
ORGANISM(S): Plasmodium Falciparum 3d7 (ncbitaxon:36329) 
2018-11-19 | MSV000083144 | MassIVE
ProteomicsIdentification of Novel Auto-antibodies in Type 1 Diabetic Patients using a High-density Protein Microarray
Type 1 diabetes mellitus (T1DM) results from immune mediated destruction of pancreatic beta cells. However, clinical and immunologic phenotypes of T1DM are variable. Several auto-antibodies including GADA, IA-2A, and ZnT8A, were identified in T1DM, but the prevalence of these auto-antibodies varied ...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-50866 | biostudies-arrayexpress
TranscriptomicsAnalysis of fetal livers from male mice after protein-restricted diet in mothers
Prenatal nutrition as influenced by nutritional status of the mother has been identified as a determinant of adult disease. Feeding low-protein diets during pregnancy in rodents is a well-established model to induce “programming” events in offspring. We hypothesized that protein restriction would in...
ORGANISM(S): Mus musculus 
2009-11-02 | E-GEOD-15280 | biostudies-arrayexpress
ProteomicsOne-dimensional capillary liquid chromatographic separation coupled with tandem mass spectrometry unveils the Escherichia coli proteome on a microarray scale.
We successfully identified the proteome expressed in Escherichia coli (E. coli) cells on a microarray scale using one-dimensional capillary liquid chromatography-tandem mass spectrometry (LC-MS/MS) with a 350 cm long, 100 microm i. d., monolithic silica-C(18) capillary column. E. coli tryptic digest...
ORGANISM(S): Escherichia Coli 
2016-07-20 | PXD004605 | JPOST Repository
GenomicsImmunological fingerprint of 4CMenB recombinant antigens via protein microarray
Immunological fingerprint of 4CMenB recombinant antigens via protein microarray
PRJNA640397 | ENA
ProteomicsA protein microarray-based analysis of S-nitrosylation
Yeast protein microarrays were utilized to investigate determinants of S-nitrosylation by biologically relevant low-mass S-nitrosothiols (SNOs). Large numbers of S-nitrosylated yeast proteins were identified after treatment with SNOs, among which those with active-site Cys thiols residing at N termi...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-19 | E-GEOD-19218 | biostudies-arrayexpress
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