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We have used a combination of RNAi based functional and molecular genomic approaches to investigate in detail two proteins required for the survival of CRC cells. Set1 has 22 samples, 10 siNeg controls, 6 siRNA transfections for FLASH and NUP62 each. Set2 has 67 samples, siNeg controls at timepoint:...
ORGANISM(S): Homo sapiens 
Ccw12p is a cell surface mannoprotein required for cell wall stability. To investigate the compensation mechanism after CCW12 deletion we analysed the global gene expression in ccw12 mutant cells. SEY6210 and MEY12A (SEY6210 deleted for CCW12) yeast strains were growth on YPD medium supplemented wit...
ORGANISM(S): Saccharomyces cerevisiae 
Candida auris is a recently found pathogenic yeast that causes systemic infections, showing a high mortality rate. In addition, C. auris has been found to be difficult to remove from the environment of health care settings, among other causes due to its high resistance to stress conditions. Moreover...
ORGANISM(S): Fungi [Candida] auris 
2025-10-23 | PXD051894 | Pride
Expression profiles were generated for eight genes located on chromosome 13 following RNAi to enable the determination of gene specific LOF RNAi signatures in the colorectal cancer cell line SW480. Triplicate transfections of SW480 cells were performed using two different siRNA duplexes correspondin...
ORGANISM(S): Homo sapiens 
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