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MetabolomicsAn ambient-temperature storage and stabilization device performs comparably to flash-frozen collection for stool metabolomics in infants

BACKGROUND: Stool metabolites provide essential insights into the function of the gut microbiome. The current gold standard for storage of stool samples for metabolomics is flash-freezing at - 80 °C which can be inconvenient and expensive. Ambient temperature storage of stool is ...

2021-01-27 | MTBLS201 | MetaboLights
MetabolomicsSerum protein N-glycosylation changes in multiple myeloma

BACKGROUND: Multiple myeloma is characterized by clonal proliferation of malignant plasma cells in the bone marrow that produce monoclonal immunoglobulins. N-glycosylation changes of these monoclonal immunoglobulins have been reported in multiple myeloma, but previous studies on...

2022-04-27 | MTBLS676 | MetaboLights
TranscriptomicsThe Rpd3 Core Complex is a Chromatin Stabilization Module
The S. cerevisiae Rpd3 large (Rpd3L) and small (Rpd3S) histone deacetylase (HDAC) complexes are prototypes for understanding transcriptional repression in eukaryotes [1]. The current view is that they function by deacetylating chromatin, thereby limiting accessibility of transcriptional factors to t...
ORGANISM(S): Saccharomyces cerevisiae 
2012-01-01 | E-GEOD-33829 | biostudies-arrayexpress
GenomicsdubTAGs enable on-demand stabilization for tunable and reversible control of endogenous protein levels
dubTAGs enable on-demand stabilization for tunable and reversible control of endogenous protein levels
PRJNA1520409 | ENA
ProteomicsAffinity capture of S. cerevisiae protein after glutaraldehyde stabilization
It remains extraordinarily challenging to elucidate endogenous protein-protein interactions and proximities within the cellular milieu. The dynamic nature and the large range of affinities of these interactions augment the difficulty of this undertaking. Among the most useful tools for extracting su...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-10-19 | PXD001262 | Pride
Budding yeast Glutaraldehyde Affinity capture 
TranscriptomicsStabilization competency signature
Comparison of gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture required for successful reprogramming mRNA profilling 4 SI clones at 5 time points, 4 SC clones at 6 time points, and 3 feeder samples.
ORGANISM(S): Mus musculus 
2013-01-01 | E-GEOD-42100 | biostudies-arrayexpress
UnknownResolving the enthalpy of protein stabilization by macromolecular crowding.
Not available
S-EPMC9942490 | biostudies-literature
GenomicsBlocking protein quality degradation leads to structural stabilization of DHFR indel variants
Blocking protein quality degradation leads to structural stabilization of DHFR indel variants
PRJNA1289146 | ENA
ProteomicsAPC/CCdc20 dependent degradation of Clb4 is all there is to astral microtubule stabilization
Coordination between sister chromatid separation and segregation is crucial for accurate chromosome partitioning to the offspring. Key to this process is the ability of mitotic spindle microtubules to respond to different molecular signals and remodel their dynamics accordingly. Based on their funct...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-19 | PXD028828 | Pride
Astral microtubule stabilization 
UnknownIn vivo protein stabilization based on fragment complementation and a split GFP system.
Not available
S-EPMC2993370 | biostudies-literature
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