Proteome integrity

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Proteomics (545)
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Technology Type

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Instrument Platform

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CHEBI ID

CHEBI:39420 (2)
CHEBI:6650 (2)
CHEBI:73138| (1)
CHEBI:167269 (1)
CHEBI:145863 (1)
CHEBI:77368 (1)
CHEBI:40822 (1)
CHEBI:192377 (1)
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CHEBI:157889 (1)
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CHEBI:194285 (1)
CHEBI:132542 (1)
CHEBI:89232 (1)

Metabolite Name

CerP(d18:1/22:0)|PC(P-16:0/P-16:0) (1)
1-docosene (1)
Tricosanoic acid (1)
DG(16:0/0:0/20:2n6) (1)
2-Tetradecanone (1)
Leukotriene E3 (1)
Pentacosanoic acid (1)
3-hydroxybutyric acid (1)
CE(16:1(9Z)) (1)
Free cholesterol (1)
Cer(d18:1/24:1(15Z)) (1)
PC(14:0/22:5(7Z,10Z,13Z,16Z,19Z)) (1)
PC(16:1(9Z)/16:0) (1)
LysoPC(22:1(13Z)) (1)
SM(d17:1/24:0) (1)
PS(20:4(5Z,8Z,11Z,14Z)/18:0) (1)
DG(16:1n7/0:0/20:2n6) (1)
LysoPC(16:0) (1)
PC(20:0/14:0) (1)
PC(18:1(9Z)/16:0) (1)
SM(d18:0/16:1(9Z)) (1)
PC(14:0/22:1(13Z)) (1)
Coenzyme Q9 (coenzyme Q9) (1)
Reduced coenzyme Q9 (coenzyme Q9H2) (1)
Coenzyme Q10 (coenzyme Q10) (1)
Reduced coenzyme Q10 (coenzyme Q10H2) (1)
SM(d18:1/24:1(15Z)) (1)
Fumarate (1)
Citrate (1)
Erucic acid (1)

First Public Date

2025 (10)
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2019 (3)
2018 (3)
2021 (2)
2020 (2)
2016 (1)
2015 (1)
2014 (1)
2012 (1)

Classification

bacteria (2)
fungi (1)
protozoa (1)

Modification

4x(15)N labeled L-arginine (2)
Not available (2)
0.984 (1)
15.99491 (1)
203.0794 (1)
2x(15)N labeled L-lysine (1)
42.01056 (1)
57.02146 (1)
79.96633 (1)
N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (22)
RNA-seq of coding RNA (15)
RNA-seq of non coding RNA from single cells (1)
Animal - One-color microarray (1)
Cell line - High-throughput sequencing (1)
RIP-seq (1)

Release Date

2025 (69)
2022 (50)
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2021 (42)
2020 (37)
2018 (33)
2024 (30)
2015 (22)
2016 (21)
2017 (21)
2014 (20)
2019 (19)
2011 (14)
2012 (13)
2013 (11)
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2026 (6)
2009 (4)
2008 (4)
2007 (2)
2006 (1)

Lab affiliation

Department of Ecology & Evolutionary Biology, University of California, Los Angeles, CA (8)
Head of the Curie Institute Mass Spectrometry Platform (4)
Keck MS & Proteomics Resource Yale School of Medicine (4)
Department of Cell Biology, Harvard Medical School, Boston, MA, USA (3)
Institute for Research in Immunology and Cancer (IRIC) Université de Montréal, Department of Chemistry, Université de Montréal, MIL campus, Montréal, H2V 0B3, Canada (3)
Medical Research Council Senior Research Fellow Associate Professor in RNA Biochemistry and Research Group Leader Centre for Synthetic and Systems Biology (SynthSys) University of Edinburgh Max Born Crescent CH Waddington Building, room 3.06 EH9 3BF Edinburgh UK (3)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (3)
Abiel Roche-Lima, MSc., PhD. Assistant Professor Director, Integrated Informatics Services core IIS-RCMI University of Puerto Rico Medical Science Campus RCMI Program PO Box 365067 San Juan, PR. 00936-5067 Phone: +1 787 758-2525 x 2194 (2)
Cell matrix biology and regenerative medicine, School of biological sciences, University of manchester (2)
Center for Genomic Integrity, Institute for Basic Science, Ulsan, Korea (2)
College of Agronomy, Qingdao Agricultural University, Qingdao Shandong, China (2)
Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 (2)
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA (2)
Department of Molecular Biosciences, University of South Florida, Tampa, FL, USA Center for Antimicrobial Resistance, University of South Florida, Tampa, FL, USA (2)
Dept. of Molecular Biosciences, University of Texas at Austin, Texas 78712 USA (2)
IMBA - Institute of Molecular Biotechnology Dr. Bohrgasse 3 1030 Vienna Austria (2)
Institute for Microbiology (2)
Institute of Biochemistry II University Hospital Building 75 Theodor-Stern-Kai 7 60590 Frankfurt (Main) (2)
Institute of Biochemistry II, Goethe University Frankfurt,Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany. (2)
Institute of Molecular Biology (IMB) (2)
Medical University of Vienna (2)
NREL (2)
Professor, Emory University School of Medicine Departments of Biochemistry and Neurology (2)
Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark (2)
Research Unit in Biology of Microorganisms (URBM), Namur Research Institute for life Sciences (Narilis), University of Namur, Namur, Belgium (2)
School of Biomedical Sciences, The University of Hong Kong (2)
Systems Biology Ireland, University College Dublin (2)
Team SOAP, CRCI2NA, Nantes Université, Inserm, CNRS, Université d’Angers, Nantes, France (2)
University Medical Center Goettingen, Department of Clinical Chemistry, Core Facility Proteomics (2)
zhejiang university (2)

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Thermal Profiling Maps Multilayered Organization of the Mitochondrial Proteome

Mitochondria execute essential metabolic, biosynthetic, and signaling functions, yet the regulatory principles governing their proteome remain incompletely understood. Here, we develop a thermal proteome profiling (TPP) workflow applied directly to purified mitochondria, enabling systematic analy...

2025-12-08 | MTBLS7386 | MetaboLights

Optimization of codon translation rates via tRNA modifications maintains proteome integrity

PRJNA279785 | ENA

Optimization of codon translation rates via tRNA modifications maintains proteome integrity

Proteins begin to fold as they emerge from translating ribosomes. The kinetics of ribosome transit along a given mRNA can influence nascent chain folding, but the extent to which individual codon translation rates impact proteome integrity remains unknown. Here, we show that slower decoding of discr...

ORGANISM(S): Caenorhabditis elegans

2015-06-04 | E-GEOD-67387 | biostudies-arrayexpress

Optimization of codon translation rates via tRNA modifications maintains proteome integrity

ORGANISM(S): Saccharomyces cerevisiae Caenorhabditis elegans

2015-06-04 | GSE67387 | GEO

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity.

Not available

S-EPMC4503807 | biostudies-literature

A proteomic view on the cell biology of Staphylococcus aureus proteome

The genome sequence is the “blue-print of life”, but proteomics is required to relate this blue-print of life to the actual physiology of living cells. Because of their low complexity – only about 2.000 proteins make a Staphylococcus aureus cell viable – bacteria are excellent model systems to ident...

ORGANISM(S): Staphylococcus aureus

2009-11-11 | E-GEOD-15060 | biostudies-arrayexpress

Heterogeneity of proteome dynamics between connective tissue phases of adult tendon.

Not available

S-EPMC7217697 | biostudies-literature

TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples.

Not available

S-EPMC7302421 | biostudies-literature

System-wide analyses reveal essential roles of N-terminal protein modification in bacterial membrane integrity.

Not available

S-EPMC9356101 | biostudies-literature

Depletion of Endothelial-Derived 2-AG Reduces Blood-Endothelial Barrier Integrity via Alteration of VE-Cadherin and the Phospho-Proteome.