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ProteomicsProteome-Wide Deconvolution of Drug Targets and Binding Sites by Lysine Reactivity Profiling
Recently, numerous efforts have been devoted to identifying drug targets and binding sites in complex proteomes, which is of great importance in modern drug discovery. In this study, we developed a robust lysine reactivity profiling method to systematically study drug-binding targets and binding sit...
ORGANISM(S): Homo Sapiens 
2023-09-28 | PXD045749 |
UnknownProteome-wide microarray-based screening of PAR-binding proteins.
Not available
S-EPMC12000866 | biostudies-literature
UnknownProteome-Wide Discovery of Degradable Proteins Using Bifunctional Molecules.
Not available
S-EPMC12670307 | biostudies-literature
UnknownProteome-Wide Profiling of Olaparib Interactors Using a Biotinylated Photoaffinity Probe.
Not available
S-EPMC11907390 | biostudies-literature
UnknownProteome-Wide Identification of RNA-Dependent Proteins in Lung Cancer Cells.
Not available
S-EPMC9776756 | biostudies-literature
TranscriptomicsRNA-Binding Protein targets in Saccharomyces cerevisiae
The vast landscape of RNA-protein interactions at the heart of post-transcriptional regulation remains largely unexplored. Indeed it is likely that, even in yeast, a substantial fraction of the regulatory RNA-binding proteins (RBPs) remain to be discovered. Systematic experimental methods can play a...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-10 | E-GEOD-22876 | biostudies-arrayexpress
UnknownProteome-Wide Analysis of Autoantibodies in Open-Angle Glaucoma in Japanese Population: A Pilot Study.
Not available
S-EPMC11940370 | biostudies-literature
UnknownVaricella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia.
Not available
S-EPMC10259006 | biostudies-literature
UnknownBOGO: A Proteome-Wide Gene Overexpression Platform for Discovering Rational Cancer Combination Therapies.
Not available
S-EPMC12424776 | biostudies-literature
TranscriptomicsLigand and Target Discovery by Fragment-Based Screening in Human Cells
Advances in the synthesis and screening of small-molecule libraries have accelerated the discovery of chemical probes for studying biological processes. Still, only a small fraction of the human proteome has chemical ligands, and the full complement of proteins with potential to be targeted by small...
ORGANISM(S): Mus musculus 
2017-01-24 | GSE90731 | GEO
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