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MetabolomicsDistinct metabolic states of a cell guide alternate fates of mutational buffering through altered proteostasis
Not available
ORGANISM(S): Escherichia coli 
ST001382 | MetabolomicsWorkbench
TranscriptomicsStress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Distinct ER Proteostasis Environments [HEK293DYG]
The unfolded protein response (UPR) maintains endoplasmic reticulum (ER) proteostasis through the activation of transcription factors such as XBP1s and ATF6. The functional consequences of these transcription factors for ER proteostasis remain poorly defined. Here, we describe methodology that enabl...
ORGANISM(S): Homo sapiens 
2013-04-23 | E-GEOD-44950 | biostudies-arrayexpress
TranscriptomicsStress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Distinct ER Proteostasis Environments [HEK293DAX]
The unfolded protein response (UPR) maintains endoplasmic reticulum (ER) proteostasis through the activation of transcription factors such as XBP1s and ATF6. The functional consequences of these transcription factors for ER proteostasis remain poorly defined. Here, we describe methodology that enabl...
ORGANISM(S): Homo sapiens 
2013-04-23 | E-GEOD-44949 | biostudies-arrayexpress
ModelsMoreno2019 - Stochastic model of G1 arrest due to proteostasis decline delimits replicative lifespan in yeast
This model is described within the paper: A G1 arrest due to proteostasis decline delimits replicative lifespan in yeast David F. Moreno, Kirsten Jenkins, Sandrine Morlot, Gilles Charvin, Attila Csikász-Nagy, Martí Aldea To be implemented in Copasi. Missing Event due to difficulties in SBML conver...
2019-11-29 | MODEL1901210001 | BioModels
GenomicsCellular proteostasis collapse in mammalian senescence
Cellular proteostasis collapse in mammalian senescence
PRJNA512837 | ENA
UnknownA chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease.
Not available
S-EPMC4255334 | biostudies-literature
UnknownSmall molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation.
Not available
S-EPMC4954754 | biostudies-literature
TranscriptomicsStress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Distinct ER Proteostasis Environments
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-04-23 | E-GEOD-44951 | biostudies-arrayexpress
GenomicsPharmacologic IRE1/XBP1s Activation Confers Targeted ER Proteostasis Reprogramming
Pharmacologic IRE1/XBP1s Activation Confers Targeted ER Proteostasis Reprogramming
PRJNA625752 | ENA
UnknownUbr1-induced selective endophagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress.
Not available
S-EPMC8888484 | biostudies-literature
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