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Rapid advances in high-throughput DNA sequencing technologies are accelerating the pace of research into personalized medicine. While methods for variant discovery and genotyping from whole genome sequencing (WGS) datasets have been well established, linking variants together into a single haplotype...
ORGANISM(S): Homo sapiens 
This proof-of-principle experiment was designed to demonstrate the feasibility of proximity labeling for RNAM-bM-^@M-^Sprotein interactions IPL-seq on 293T-Rex expressing MSA-SNRPN70 (sample) or NFH-SNRPN70 (control)
ORGANISM(S): Homo sapiens 
Off-the-shelf proximity labeling
Bioluminescence-activated proximity labeling for spatial multi-omics
RNA proximity labeling in log phase Caulobacter crescentus NA1000
Proximity of oligodendrocytes remodels astrocytes' transcriptome
Activation of the NACHT, LRR family pyrin domain containing 3 (NLRP3) inflammasome complex is an essential innate immune signalling mechanism. To reveal how NLRP3 inflammasome assembly and activation are controlled, in particular by components of the ubiquitin system, proximity labelling, affinity p...
ORGANISM(S): Homo sapiens (Human) 
2024-04-24 | PXD045862 | Pride
Proximity labeling approaches have been widely utilized to define protein interactomes. Due to the inherent promiscuity of proximity labeling using TurboID-based approaches, identification and adoption of appropriate labeling controls is a pivotal step to mitigate background interference and enhance...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD061564 | Pride
Proximity labeling approaches have been widely utilized to define protein interactomes. Due to the inherent promiscuity of proximity labeling using TurboID-based approaches, identification and adoption of appropriate labeling controls is a pivotal step to mitigate background interference and enhance...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD061540 | Pride
Proximity labeling approaches have been widely utilized to define protein interactomes. Due to the inherent promiscuity of proximity labeling using TurboID-based approaches, identification and adoption of appropriate labeling controls is a pivotal step to mitigate background interference and enhance...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD061566 | Pride
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