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ProteomicsControl of TurboID-dependent biotinylation intensity in proximity ligation screens
Proximity biotinylation screens are a widely used strategy for the unbiased identification of interacting or vicinal proteins. The latest generation biotin ligase TurboID has broadened the range of potential applications, as this ligase promotes an intense and faster biotinylation, even in subcellul...
ORGANISM(S): Homo sapiens (Human) 
2023-03-29 | PXD040302 | Pride
Biotinylation Proximity ligation screens Protein-protein interactions Proteomics 
UnknownSystematic Quantification of Synapses in Primary Neuronal Culture.
Not available
S-EPMC7516133 | biostudies-literature
GenomicsGenome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model
The enhancer-promoter looping model, in which enhancers activate their target genes via physical contact, has been the dominant hypothesis in the field for decades. However, a systematic testing of this hypothesis has not been conducted, primarily due to the absence of suitable experimental techniqu...
ORGANISM(S): Homo sapiens 
2023-12-24 | GSE225087 | GEO
UnknownESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling.
Not available
S-EPMC9899276 | biostudies-literature
UnknownA genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model.
Not available
S-EPMC11651654 | biostudies-literature
UnknownFbxo45 Binds SPRY Motifs in the Extracellular Domain of N-Cadherin and Regulates Neuron Migration during Brain Development.
Not available
S-EPMC7324847 | biostudies-literature
ProteomicsESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling
STING is an intracellular sensor of cyclic di-nucleotides involved in response to pathogen- or self-derived DNA that induces protective immunity, or if dysregulated, autoimmunity. STING trafficking is tightly linked to its activity. We aimed to systematically characterize genes regulating STING traf...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-12-14 | MSV000090900 | MassIVE
UnknownThe DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA viruses.
Not available
S-EPMC9638865 | biostudies-literature
UnknownCalcitonin Receptor-Zonula Occludens-1 Interaction Is Critical for Calcitonin-Stimulated Prostate Cancer Metastasis.
Not available
S-EPMC4775073 | biostudies-literature
UnknownThe effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis.
Not available
S-EPMC7111284 | biostudies-literature
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