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ProteomicsProtein-interaction network reveals a role of Prp19 splicing factor in transcription of both intron-containing and intron-less genes
We have previously demonstrated that the transcription-dependent interaction of the promoter and terminator ends of a gene, which results in the formation of a gene loop, is facilitated by the interaction of the general transcription factor TFIIB with the CF1, CPF and Rat1 termination complexes. To ...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2026-02-11 | PXD061187 | Pride
Rnapii Chromatin remodeling Yeast Prp19 splicing factor 
GenomicsProtein-interaction network reveals a role of Prp19 splicing factor in transcription of both intron-containing and intron-less genes
Protein-interaction network reveals a role of Prp19 splicing factor in transcription of both intron-containing and intron-less genes
PRJNA1250287 | ENA
OtherProtein-interaction network reveals a role of Prp19 splicing factor in transcription of both intron-containing and intron-less genes
We have previously demonstrated that the transcription-dependent interaction of the promoter and terminator ends of a gene, which results in the formation of a gene loop, is facilitated by the interaction of the general transcription factor TFIIB with the CF1, CPF and Rat1 termination complexes. To ...
ORGANISM(S): Saccharomyces cerevisiae 
2026-02-11 | GSE294484 | GEO
UnknownProtein-interaction network analysis reveals the role of Prp19 splicing factor in transcription of both intron-containing and intron-lacking genes.
Not available
S-EPMC12935305 | biostudies-literature
UnknownA distinct complex of PRP19-related and trypanosomatid-specific proteins is required for pre-mRNA splicing in trypanosomes.
Not available
S-EPMC8682746 | biostudies-literature
TranscriptomicsThe faint sausage gene encodes a subunit of the spliceosome-activating Prp19 complex and is required for tracheal branching morphogenesis in Drosophila
Morphogenesis requires the dynamic regulation of gene expression, including transcription, mRNA maturation and translation. Dysfunction of general components of the splicing machinery can cause surprisingly specific phenotypes, but the basis for these cell-type specific effects is not clear. Here we...
ORGANISM(S): Drosophila melanogaster 
2016-11-18 | E-MTAB-5069 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of budding yeast wild type (BY4741) and prp45(1-169) mutant
Prp45 is a budding yeast NineTeen-Complex associated factor, which plays a role in pre-mRNA splicing. In addition to its documented involvement in the second step of splicing, here we show that it is important in the early stages of co-transcriptional spliceosome assembly as well. To determine the o...
ORGANISM(S): Saccharomyces cerevisiae 
2017-02-10 | E-MTAB-5149 | biostudies-arrayexpress
UnknownThe Prp19 WD40 domain contains a conserved protein interaction region essential for its function.
Not available
S-EPMC2871033 | biostudies-literature
UnknownPrp19 Is an Independent Prognostic Marker and Promotes Neuroblastoma Metastasis by Regulating the Hippo-YAP Signaling Pathway.
Not available
S-EPMC7667276 | biostudies-literature
UnknownSNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly.
Not available
S-EPMC1310963 | biostudies-literature
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