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GenomicsFBXW7/GSK3β-mediated degradation of PRR11 inhibits RCC progression via oxidative DNA damage
FBXW7/GSK3β-mediated degradation of PRR11 inhibits RCC progression via oxidative DNA damage
PRJNA1100454 | ENA
TranscriptomicsFBXW7/GSK3β-mediated degradation of PRR11 inhibits RCC progression via oxidative DNA damage
In our previous study, we reported that proline-rich 11 (PRR11) expression is upregulated in renal cell carcinoma (RCC) and is involved in the regulation of cell cycle and apoptosis. Here, we continued to investigate the pro-carcinogenic role of PRR11 and found that PRR11 regulates oxidative DNA dam...
ORGANISM(S): Homo sapiens 
2025-03-19 | GSE263951 | GEO
UnknownPRR11 promotes ccRCC tumorigenesis by regulating E2F1 stability.
Not available
S-EPMC8525590 | biostudies-literature
GenomicsHEDGEHOG/GLI Modulates The PRR11-SKA2 Bidirectional Transcription Unit in Lung Squamous Cell Carcinomas
HEDGEHOG/GLI Modulates The PRR11-SKA2 Bidirectional Transcription Unit in Lung Squamous Cell Carcinomas
PRJNA675892 | ENA
TranscriptomicsHEDGEHOG/GLI Modulates The PRR11-SKA2 Bidirectional Transcription Unit in Lung Squamous Cell Carcinomas
We previously demonstrated that proline-rich protein 11 (PRR11) and spindle and kinetochore associated 2 (SKA2) constituted a head-to-head gene pair driven by a prototypical bidirectional promoter, and this gene pair synergistically promoted the development of non-small-cell lung cancer. However, th...
ORGANISM(S): Homo sapiens 
2022-11-10 | GSE161226 | GEO
UnknownThe prognostic potential and oncogenic effects of PRR11 expression in hilar cholangiocarcinoma.
Not available
S-EPMC4653015 | biostudies-literature
UnknownPRR11 Is a Prognostic Marker and Potential Oncogene in Patients with Gastric Cancer.
Not available
S-EPMC4529228 | biostudies-literature
UnknownPRR11 is a prognostic biomarker and correlates with immune infiltrates in bladder urothelial carcinoma.
Not available
S-EPMC9899238 | biostudies-literature
UnknownPRR11 and SKA2 gene pair is overexpressed and regulated by p53 in breast cancer.
Not available
S-EPMC6443325 | biostudies-literature
UnknownPRR11 Promotes Bladder Cancer Growth and Metastasis by Facilitating G1/S Progression and Epithelial-Mesenchymal Transition.
Not available
S-EPMC11891932 | biostudies-literature
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