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ProteomicsSystematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow
Cell-to-cell communications are critical determinants of pathophysiological phenotypes, but methodologies for their systematic elucidation are lacking. Herein, we propose an approach for the Systematic Elucidation and Assessment of Regulatory Cell-to-cell Interaction Networks (SEARCHIN) to elucidat...
ORGANISM(S): Rattus rattus (Black rat) 
2021-09-09 | PXD021773 | Pride
Searchin Bioinformatics Death receptor-6 Als Motor neuron Non-cell autonomous Mutant sod1 
TranscriptomicsMouse ES-derived motor neurons (ES-MN) exposed to SOD1 mutant mouse astrocyte conditioned media
This datased was used to obtain a genome-wide expression signature for the early response of mouse motor neurons to mutant SOD1 astrocytes conditioned media. Neurons, far from living in isolation, are surrounded by a host of other neuronal and non-neuronal cells, such as astrocytes. The latter enter...
ORGANISM(S): Mus musculus 
2014-12-17 | E-GEOD-49023 | biostudies-arrayexpress
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