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GenomicsExamining alterations in gene expression of PC3-wt (PSMA -ve) vs PC3-PSMA (PSMA +ve) cells
Examining alterations in gene expression of PC3-wt (PSMA -ve) vs PC3-PSMA (PSMA +ve) cells
PRJNA412566 | ENA
GenomicsS. venezuelae psmA mutant
Verification of psmA mutant of Streptomyces venezuelae
PRJEB92325 | ENA
GenomicsExamining alterations in gene expression of LNCaP-Ctrl (PSMA +ve) vs LNCaP-KD (PSMA -ve) cells
Examining alterations in gene expression of LNCaP-Ctrl (PSMA +ve) vs LNCaP-KD (PSMA -ve) cells
PRJNA412567 | ENA
GenomicsTranscriptomics of psmA mutant
RNA-seq comparison of psmA mutant and wild type of Streptomyces venezuelae
PRJEB92404 | ENA
TranscriptomicsExamining alterations in gene expression of PC3-wt (PSMA -ve) vs PC3-PSMA (PSMA +ve) cells
The biological role of PSMA, a biomarker expressed in prostate cancer and by the neovasculature of solid tumors, remains unknown. Although PSMA processes folates in our duodenum, and in the brain cleaves NAAG to control neuronal signaling, little is known about its role in cancer. We used microarray...
ORGANISM(S): Homo sapiens 
2017-11-11 | GSE104418 | GEO
GenomicsReversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer.
Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer.
PRJNA843461 | ENA
ProteomicsMechanisms of Resistance to Prostate-Specific Membrane Antigen-Targeted Radioligand Therapy in a Mouse Model of Prostate Cancer
Purpose: Prostate-specific membrane antigen-targeted radioligand therapy (PSMA-RLT) is effective against prostate cancer (PCa), but all patients relapse eventually. Poor understanding of the underlying resistance mechanisms represents a key barrier to development of more effective RLT. We investigat...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-04 | MSV000086408 | MassIVE
GenomicsATGL-driven lipolysis defines a targetable metabolic vulnerability in PSMA-high prostate cancer
ATGL-driven lipolysis defines a targetable metabolic vulnerability in PSMA-high prostate cancer
PRJNA1295534 | ENA
TranscriptomicsExamining alterations in gene expression of LNCaP-Ctrl (PSMA +ve) vs LNCaP-KD (PSMA -ve) cells
The biological role of PSMA, a biomarker expressed in prostate cancer and by the neovasculature of solid tumors, remains unknown. Although PSMA processes folates in our duodenum, and in the brain cleaves NAAG to control neuronal signaling, little is known about its role in cancer. We used microarray...
ORGANISM(S): Homo sapiens 
2017-11-11 | GSE104417 | GEO
Methylation profilingReversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer.
Purpose: Prostate-specific membrane antigen (PSMA) is a cell surface protein expressed in prostate cancer. PSMA targeted imaging and therapeutic approaches have shown clinical benefit, but there are limited data on the heterogeneity of PSMA tissue expression in metastatic castration-resistant prosta...
ORGANISM(S): Homo sapiens 
2023-05-03 | GSE205056 | GEO
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