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TranscriptomicsBeta-catenin status in pediatric medulloblastomas
Medulloblastoma is the most frequent malignant pediatric brain tumor. Considerable efforts are dedicated to identify markers that help to refine treatment strategies. The activation of the Wnt/beta-catenin pathway occurs in 10-15% of medulloblastomas and has been recently described as a marker for f...
ORGANISM(S): Homo sapiens 
2009-02-02 | E-GEOD-12992 | biostudies-arrayexpress
TranscriptomicsPemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma
We devised a high-throughput, cell-based assay to identify novel therapeutic compounds to treat Group3 medulloblastoma (G3 MB). Mouse G3 MBs, grown as neurospheres, were screened against a library of approximately 7,000 compounds including FDA-approved drugs. We identified two FDA-approved drugs, ...
ORGANISM(S): Mus musculus 
2014-04-15 | E-GEOD-46406 | biostudies-arrayexpress
UnknownClinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.
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S-EPMC6075859 | biostudies-literature
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