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TranscriptomicsGene expression profiling of GPR86 (P2RY13) KO mice
The purinergic receptor P2Y13 (P2RY13) has been shown to play a role in the uptake of holo-HDL particles in in vitro hepatocyte experiments. In order to determine the role of P2Y13 in lipoprotein metabolism in vivo, we ablated the expression of this gene in mice and found that P2Y13 knockout mice ha...
ORGANISM(S): Mus musculus 
2010-09-10 | E-GEOD-20920 | biostudies-arrayexpress
UnknownComprehensive genetic testing for female and male infertility using next-generation sequencing.
Not available
S-EPMC6086787 | biostudies-literature
TranscriptomicsThe gamma secretase inhibitor MRK-003 attenuates pancreatic cancer growth in preclinical models
Pancreatic ductal adenocarcinoma (PDAC) is a nearly uniformly lethal malignancy, with most patients facing an adverse clinical outcome. Given the pivotal role of aberrant Notch signaling in the initiation and progression of PDAC, we investigated the effect of MRK-003, a potent and selective γ-secre...
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-37645 | biostudies-arrayexpress
UnknownEvaluating genetic ancestry and self-reported ethnicity in the context of carrier screening.
Not available
S-EPMC5704547 | biostudies-literature
UnknownSorafenib and irinotecan (NEXIRI) as second- or later-line treatment for patients with metastatic colorectal cancer and KRAS-mutated tumours: a multicentre Phase I/II trial.
Not available
S-EPMC3950852 | biostudies-literature
UnknownEarly ctDNA and Survival in Metastatic Colorectal Cancer Treated With Immune Checkpoint Inhibitors: A Secondary Analysis of the SAMCO-PRODIGE 54 Randomized Clinical Trial.
Not available
S-EPMC12177728 | biostudies-literature
UnknownAvelumab vs Standard Second-Line Chemotherapy in Patients With Metastatic Colorectal Cancer and Microsatellite Instability: A Randomized Clinical Trial.
Not available
S-EPMC10401392 | biostudies-literature
UnknownPreliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Not available
S-EPMC8360544 | biostudies-literature
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
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