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UnknownUsing transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients.
Not available
S-EPMC2483684 | biostudies-literature
TranscriptomicsTranscription profiling of human liver transplant patients reveals a signature that could discriminate tolerant recipients from immunosuppression-dependent patients
mmunosuppressive drugs can be completely withdrawn in up to 20% of liver transplant recipients, commonly referred to as ‘operationally’ tolerant. Immune characterization of these patients, however, has not been performed in detail, and we lack tests capable of identifying tolerant patients among...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-11881 | biostudies-arrayexpress
TranscriptomicsComparative Transcriptional and Phenotypic Peripheral Blood Analysis of Kidney Recipients under Cyclosporin A or Sirolimus Monotherapy
Due to its low level of nephrotoxicity and capacity to harness tolerogenic pathways, sirolimus (SRL) has been proposed as an alternative to calcineurin inhibitors in transplantation. The exact mechanisms underlying its unique immunosuppressive profile in humans, however, are still not well understoo...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-22224 | biostudies-arrayexpress
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