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TranscriptomicsTranscription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice
RNA-Seq was performed on pancreatic islets from four transgenic mouse strains affecting LKB1 and AMPK. A conditional LKB1 knockout strain was generated. Double conditional knockouts for AMPK alpha1 and AMPK alpha2 were also generated. These conditional strains were crossed with RIP-Cre (driven by ra...
ORGANISM(S): Mus musculus 
2014-10-25 | E-MTAB-2791 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by high throughput sequencing of pancreatic islets from R299Q AMPK gamma 2 knock-in mice
RNA-Seq to investigate significant transcriptional differences underlying the defective glucose-stimulated insulin secretion of R299Q AMPK g2 knock-in mice compared to wild-type littermate controls.
ORGANISM(S): Mus musculus 
2016-05-20 | E-MTAB-3938 | biostudies-arrayexpress
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