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GenomicsHDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibroadipogenic progenitors in dystrophic muscles
Fibro-adipogenic progenitors (FAPs) are emerging cellular components of the skeletal muscle regenerative environment. The alternative functional phenotype of FAPs - either supportive of muscle regeneration or promoting fibro-adipogenic degeneration M-bM-^@M-^S is a key determinant in the pathogenesi...
ORGANISM(S): Mus musculus 
2014-04-02 | E-GEOD-52062 | biostudies-arrayexpress
TranscriptomicsSmall RNA-sequencing of Fibro-Adipogenic Progenitors (FAPs) upon Histone Deacetylase inhibition in young mdx mice
Fibro-adipogenic progenitors (FAPs) are emerging cellular components of the skeletal muscle regenerative environment. The alternative functional phenotype of FAPs - either supportive of muscle regeneration or promoting fibro-adipogenic degeneration - is a key determinant in the pathogenesis of muscu...
ORGANISM(S): Mus musculus 
2014-04-23 | E-GEOD-51933 | biostudies-arrayexpress
UnknownTBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells.
Not available
S-EPMC4775216 | biostudies-literature
ProteomicsLncRNA EPR-induced METTL7A1 modulates target gene translation
EPR is a long non-coding RNA (lncRNA) that controls cell proliferation in mammary gland cells by regulating gene transcription. Here, we report on Mettl7a1 as a direct target of EPR. We show that EPR induces Mettl7a1 transcription by rewiring three-dimensional chromatin interactions at the Mettl7a1 ...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD034398 | Pride
Lncerna Rna binding protein Translation 
UnknownSerpinE1 drives a cell-autonomous pathogenic signaling in Hutchinson-Gilford progeria syndrome.
Not available
S-EPMC9418244 | biostudies-literature
UnknownLncRNA EPR-induced METTL7A1 modulates target gene translation.
Not available
S-EPMC9303270 | biostudies-literature
UnknownSignal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex.
Not available
S-EPMC3261556 | biostudies-literature
UnknownHDAC inhibitors tune miRNAs in extracellular vesicles of dystrophic muscle-resident mesenchymal cells.
Not available
S-EPMC7507515 | biostudies-literature
UnknownLncRNA EPR regulates intestinal mucus production and protects against inflammation and tumorigenesis.
Not available
S-EPMC10250242 | biostudies-literature
TranscriptomicsTranscription profiling of human adipose tissue using an expanded patient cohort
Obesity is a risk factor for numerous metabolic disorders; however, not all obese individuals are prone to insulin resistance. The central aim of this study was to identify molecular pathways directly related to insulin resistance independent of BMI in obesity. We sought to determine the gene expre...
ORGANISM(S): Homo sapiens 
2010-04-07 | E-GEOD-20950 | biostudies-arrayexpress
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