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TranscriptomicsTranscription profiling of two human cellular models of erythroid differentiation: K562 erythroid-leukemia cells treated with 1uM arabinofuranosyl-cytosine (AraC), and CD34+ stem cells treated with 7U/ml erythropoietin
In this study we investigated two cellular models of erythroid differentiation: K562 erythroid-leukemia cells treated with 1uM arabinofuranosyl-cytosine (AraC), and CD34+ stem cells treated with 7U/ml erythropoietin. Time course experiments were performed in both analysed models. Total RNAs were iso...
ORGANISM(S): Homo sapiens 
2006-12-31 | E-MEXP-296 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MCF7 cell response toCimicfuga racemosa (black cohosh)
Extracts from the rhizome of Cimicifuga racemosa (black cohosh) are increasingly popular as herbal alternative to hormone replacement therapy (HRT) for the alleviation of postmenopausal disorders. However, the molecular mode of action and the active principles are presently not clear. Previously pub...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6800 | biostudies-arrayexpress
TranscriptomicsGene expression in rectal epithelia of cystic fibrosis patients
Gene expression profiles were recorded from rectal suction specimens of Cystic Fibrosis (CF) patients, carrying the CF-specific D508 mutated CFTR-allele. These profiles were compared with gene expression profiles from rectal suction specimens of non-CF subjects (control). We used Affymetrix GeneChi...
ORGANISM(S): Homo sapiens 
2013-11-28 | E-GEOD-15568 | biostudies-arrayexpress
TranscriptomicsSuppression of antitumor immunity by the oncometabolite 2-hydroxyglutarate
Isocitrate dehydrogenase (IDH) mutations, a hallmark of gliomagenesis, result in the production of the oncometabolite R-2-hydroxyglutarate (R-2-HG) which is thought to promote tumorigenesis via DNA methylation. Here we identify an additional immunosuppressive activity of R-2-HG: Tumor cell-derived R...
ORGANISM(S): Homo sapiens 
2016-07-27 | E-GEOD-84849 | biostudies-arrayexpress
UnknownG3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Not available
S-EPMC7868890 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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