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MetabolomicsEffect of NAC154 transcription factor overexpression on the field grown poplar stem wood metabolome
Several xylem-associated regulatory genes have been identified that control processes associated with wood formation in poplar. Prominent among these are the NAC domain transcription factors (NACs). We evaluated the putative involvement of Populus NAC154, a co-ortholog of the Arabidopsis gene SND2, ...
2015-01-31 | MTBLS119 | MetaboLights
TranscriptomicsA global network of transcription factors, involving E2A, EBF1 and FOXO1, that orchestrates the B cell fate
It is now established that the transcription factors E2A, EBF1 and FoxoM-BM- 1 play critical roles in B cell development. Here we show that E2A and EBF1 bound regulatory elements present in the Foxo1 locus. E2A and EBF1 as well as E2A and Foxo1, in turn, were wired together by a vast spectrum of cis...
ORGANISM(S): Mus musculus 
2010-06-12 | E-GEOD-21978 | biostudies-arrayexpress
MetabolomicsSystematic identification of metabolites controlling gene expression in E. coli
Metabolism controls gene expression through allosteric interactions between metabolites and transcription factors. These interactions are usually measured with in vitro assays, but there are no methods to identify them at a genome-scale in vivo. Here we show that dynamic transcriptome and metabolome...
2019-08-23 | MTBLS1044 | MetaboLights
TranscriptomicsTwo transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [ChIP-chip data]
Because iron toxicity and deficiency are equally life threatening, maintaining intracellular iron levels within a narrow optimal range is critical for nearly all known organisms. However, regulatory mechanisms that establish homeostasis are not well understood in organisms that dwell in environments...
ORGANISM(S): Halobacterium sp. NRC-1 
2011-06-02 | E-GEOD-29705 | biostudies-arrayexpress
TranscriptomicsThe transcription factors Pcr1 and Atf1 have distinct roles in stress- and Sty1-dependent gene regulation
Gene expression was monitored in the knockout of two transcription factors, Pcr1 and Atf1, in the presence and absence of oxidative stress induced by KCl.
ORGANISM(S): Schizosaccharomyces pombe 
2008-03-03 | E-TABM-447 | biostudies-arrayexpress
GenomicsComparative transcriptomics of Aspergillus niger when deleted or overexpressed for the putative transcription factors MjkA, MjkB and the histon deactelyase HdaX
Comparative transcriptomics of Aspergillus niger when deleted or overexpressed for the putative transcription factors MjkA, MjkB and the histon deactelyase HdaX
PRJNA488723 | ENA
GenomicsCell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells [new ChIP-Seq samples]
Cellular diversity in a multicellular organism like the human is achieved in part by distinct programs of gene expression at the level of transcription, which in turn are mediated by transcription factors (TFs). However, there are few systematic studies of the genomic binding of different types of T...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-32692 | biostudies-arrayexpress
GenomicsIntegrative Genomic Analyses Reveal Putative Cell Type-specific Targets of theDrosophilaEts Transcription Factor Pointed
Integrative Genomic Analyses Reveal Putative Cell Type-specific Targets of theDrosophilaEts Transcription Factor Pointed
PRJNA1036706 | ENA
UnknownIdentification of putative regulatory regions and transcription factors associated with intramuscular fat content traits.
Not available
S-EPMC6020320 | biostudies-literature
ProteomicsEstablishment of a novel in vitro transcription assay
RNA Polymerase II (Pol II) transcriptional recycling is an underappreciated mechanism for which the required factors and contributions to overall gene expression levels are poorly understood. We describe an in vitro methodology facilitating unbiased identification of putative RNA Pol II transcriptio...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD027143 | Pride
Lc-ms/ms Transcription 
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