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Proliferative vitreoretinopathy (PVR) is a severe vision-threatening disorder characterized by the formation of cicatricial fibrous membranes leading to traction retinal detachment. As the pathophysiology remains unclear, there has been no effective therapeutic approach to date other than vitreoreti...
ORGANISM(S): Homo sapiens 
Expression data from adult myocardium of ToF-PVR patients undergoing pulmonary valve replacement
A Pvr–AP-1–Mmp1 signaling pathway is activated in astrocytes upon traumatic brain injury
Traumatic brain injury (TBI) caused by external mechanical forces is a major health burden worldwide, but the underlying mechanism in glia remains largely unclear. We report herein that Drosophila adults exhibit a defective blood-brain-barrier (BBB), elevated innate immune responses, and appear to b...
ORGANISM(S): Drosophila melanogaster 
2024-06-30 | GSE263447 | GEO
Increased PVR Expression on Bone Marrow Macrophages May Promote Resistance to TIGIT Blockade in Multiple Myeloma
Targeting PVR (CD155) in cancer therapy (PRJCA033825)
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