Sort   by:  
 Page size 
ProteomicsmTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase
Supporting MS data for paper (DOI:10.1016/j.celrep.2024.115179) by Pham, B. et al., titled "mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase". Related to Table S1 - HEK293 - degradomics (HA-2-165 | Unimod:35; 2016; 4 | 126 - Neg Ctrl (WT cells...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-29 | MSV000095724 | MassIVE
ProteomicsNovel genetic mutations in pyrimidine salvage pathway enzymes from Cryptococcus neoformans contribute to reduced susceptibility against 5-fluorocytosine
The most common cause of cryptococcal meningitis is Cryptococcus neoformans. The addition of 5-fluorocytosine to the treatment of patient with this potentially fatal infection significantly improves disease outcome. However, developing resistance to this drug is a serious problem in patient manageme...
ORGANISM(S): Cryptococcus neoformans var. grubii Cryptococcus neoformans var. neoformans 
2024-07-29 | PXD044249 | Pride
Pyrimidine salvage pathway Proteomics Cryptococcus neoformans Resistance 5-fluorocytosine 
GenomicsNitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
PRJNA1427716 | ENA
UnknownmTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase.
Not available
S-EPMC11840829 | biostudies-literature
TranscriptomicsNitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
Stable isotope tracing assays track few metabolites, yet cells use many nutrients to sustain nitrogen metabolism. Here, we create a platform for tracing 30 nitrogen isotope-labeled metabolites in parallel to enable a system-level understanding of cellular nitrogen metabolism. This platform reveals t...
ORGANISM(S): Homo sapiens 
2026-02-24 | GSE320388 | GEO
UnknownGenetic dissection of pyrimidine biosynthesis and salvage in Leishmania donovani.
Not available
S-EPMC3339959 | biostudies-literature
GenomicsTargeting plasticity in the pyrimidine synthesis pathway potentiates macrophage-mediated phagocytosis in pancreatic cancer models
Targeting plasticity in the pyrimidine synthesis pathway potentiates macrophage-mediated phagocytosis in pancreatic cancer models
PRJNA1093055 | ENA
TranscriptomicsTranscription profiling of primary mouse embryonic fibroblasts (MEF) in response to serum
Current methods to analyze gene expression measure steady-state levels of mRNA. In order to specifically analyze mRNA transcription, a technique has been developed that can be applied in-vivo. The technique is referred with the acronym NIAC-NTR (Non Invasive Application and Capture of Newly Transcri...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6697 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse contralateral kidneys in response to ischemia reperfusion injury
Current methods to analyze gene expression measure steady-state levels of mRNA. In order to specifically analyze mRNA transcription, a technique has been developed that can be applied in-vivo in intact cells and animals. The technique is referred with the acronym NIAC-NTR (Non Invasive Application a...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6698 | biostudies-arrayexpress
UnknownRetinoblastoma vulnerability to combined de novo and salvage pyrimidine ribonucleotide synthesis pharmacologic blockage.
Not available
S-EPMC10851301 | biostudies-literature
Sort   by:  
 Page size