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CRISPR-Cas immune systems function to defend prokaryotes against potentially harmful mobile genetic elements including viruses and plasmids. The multiple CRISPR-Cas systems (Types I, II, III) each recognize and target destruction of foreign invader nucleic acids via structurally and functionally div...
ORGANISM(S): Pyrococcus furiosus 
Advances in mass spectrometry (MS) have enabled high-throughput analysis of proteomes in biological systems. The state-of-the-art MS data analysis relies on database search algorithms to quantify proteins by identifying peptide-spectrum matches (PSMs), which convert mass spectra to peptide sequences...
ORGANISM(S): Pyrococcus furiosus 
2021-09-21 | PXD028558 | Pride
A hybrid array setup containing WT Pyrococcus furiosus genes plus heterologous genes for engineered pathway producing 3HP from maltose and CO2 was used to study the impact of heterlogous pathway on native metabolic systems Four different experiments were run: 1) Pfu WT vs Pfu COM1; 2) Pfu COM1 vs MW...
ORGANISM(S): Pyrococcus furiosus DSM 3638 Pyrococcus furiosus COM1 Pyrococcus furiosus 
2015-03-07 | GSE66643 | GEO
Pyrococcus furiosus crRNAs associated with Cmr, Csa and Cst CRISPR-Cas systems
Mass spectrometry-based proteomics data, obtained experimentally or via public repositories, remains challenging to analyze. This challenge is particularly felt when re-analysing or re-purposing public data sets, endeavours that otherwise hold great potential. PeptideShaker is an open source system ...
ORGANISM(S): Pyrococcus furiosus 
2014-06-24 | PXD001077 | Pride
CRISPR-Cas immune systems function to defend prokaryotes against potentially harmful mobile genetic elements including viruses and plasmids. The multiple CRISPR-Cas systems (Types I, II, III) each recognize and target destruction of foreign invader nucleic acids via structurally and functionally div...
ORGANISM(S): Pyrococcus furiosus 
2015-07-10 | GSE65781 | GEO
Transcriptomic Evaluation of Pyrococcus furiosus strains engineered to produce 3HP
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