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TranscriptomicsExpression data from PonA stimulated transfected U373 Cells
Induction of proximal components of the PI3-K/AKT pathway stimulates the expression of several genes, including several genes in the JAK/STAT pathway, documenting a crosstalk between these two important pathways. These changes were accompnied by nuclear translocation of certain transcription factors...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-18798 | biostudies-arrayexpress
TranscriptomicsAcute lymphoblastic leukemia
This SuperSeries is composed of the following subset Series: GSE23998: Gene expression profiles of splenocytes of CD22DE12 transgenic mice GSE24000: Gene expression profiles of ALL cells Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-09-10 | E-GEOD-24001 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of ALL cells
Using using ATLAS cDNA expression arrays, we performed gene expression profiling of primary leukemia cells from 31 infants and 30 non-infant children (pediatric patients) with ALL to determine if any of these signature genes are differentially expressed in infant ALL vs. pediatric ALL. Reduced expr...
ORGANISM(S): Homo sapiens 
2010-09-10 | E-GEOD-24000 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of splenocytes of CD22DE12 transgenic mice
Splenocytes from nontransgenic control mice and transgenic mice were isolated and their gene expression profiles were compared to determine if the expression of the transgene results in any changes in regulation of gene expression. 12 differentially expressed genes were classified as the most discri...
ORGANISM(S): Mus musculus 
2010-09-10 | E-GEOD-23998 | biostudies-arrayexpress
TranscriptomicsmRNA expression data from BCR-ABL, MYC and CD22DE12 transgenic mouse models
Leukemic splenocytes from these commercial transgenic mice that developed fatal leukemia with massive splenomegaly were isolated at the time of the necropsy and subjected to gene expression profiling and phosphoprotein profiling in side by side comparison with CD22DE12-Tg BPL or CD22DE12_BCR-ABL dou...
ORGANISM(S): Mus musculus 
2015-06-25 | E-GEOD-58872 | biostudies-arrayexpress
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