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PKA signaling plays important functions during mouse spermatogenesis and for the regulation of sperm motility. The efficiency of PKA signaling is regulated partly by its binding protein A-kinase anchoring protein (AKAP) family. Mature mouse sperm contain several AKAPs, of which AKAP3 and AKAP4 are...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-14 | PXD016928 | Pride
Proteostasis regulated by RPL39L maintains mouse spermatogenesis
ORGANISM(S): Mus Musculus 
2021-10-22 | PXD029274 |
Lithocholic acid (LCA), accumulated in mammals during calorie restriction (CR), can activate AMP-activated protein kinase (AMPK) and slow down ageing1. However, how LCA is signalled to activate AMPK and elicit the biological effects is unclear. Here, we show that LCA can enhance the activity of sirt...
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-09-16 | PXD056134 |
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