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ProteomicsProteomic of Chaihu-Shugan-San (CSS), Rou Gan, and Shu Gan treat chronic unpredictable mild stress (CUMS) rat with Tandem Mass Tags
Chaihu-Shugan-San (CSS) is a classical prescription used to treat depression. According to the traditional Chinese medicine (TCM) principle, the 2 decomposed recipes in CSS exert synergistic effects, including Shu Gan (stagnated Gan-Qi dispersion) and Rou Gan (pain alleviation). However, the specifi...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD024436 | Pride
Chaihu-shugan-san Hippocampus Depression Proteomics Traditional chinese medicine 
ProteomicsSingle-cell quantitative proteomic analysis of oocyte maturation revealed high heterogeneities in human in vitro matured oocytes
In this study we investigated the protein expression patterns during human oocyte in vitro and in vivo maturation (IVO) by single-cell quantitative proteomic analysis of 36 human oocytes. Among 2,094 proteins quantified in 34 oocytes (GV: 11 oocytes, IVM: 12 oocytes, IVO: 11 oocytes), 224 were diffe...
ORGANISM(S): Homo sapiens (Human) 
2022-08-02 | PXD023366 | Pride
Human oocyte maturation Single cell proteomics 
ProteomicsStudying the role of RPL39L in mouse spermatogenesis
Proteostasis regulated by RPL39L maintains mouse spermatogenesis
ORGANISM(S): Mus Musculus 
2021-10-22 | PXD029274 |
ProteomicsPhosphoroteome of Scutellaria baicalensis
3289 phosphopeptides were identified and mapped to 1472 proteins that are comparable by phosphoproteomics analysis and annotated in COG/KOG, Domain, KEGG and GO database, respectively
ORGANISM(S): Scutellaria Baicalensis 
2023-04-18 | PXD041603 |
ProteomicsProteome of Scutellaria baicalensis Georgi
Proteome of Scutellaria baicalensis Georgi from multiple tissues
ORGANISM(S): Scutellaria Baicalensis 
2023-04-18 | PXD041602 |
ProteomicsLenalidomide-induced pure red cell aplasia analysis
The RVd therapy, combining lenalidomide, bortezomib, and dexamethasone, is a mainstay treatment for multiple myeloma. A multiple myeloma patient developed pure red cell aplasia (PRCA) following RVd treatment, despite the absence of common PRCA triggers. In vitro analyses revealed lenalidomide as a p...
ORGANISM(S): Homo Sapiens 
2024-09-03 | PXD055495 |
Proteomicsc-JUN interacte with NuRD complex to regulate chromatin remodeling
detect c-JUN interaction proteins in humanembryonic stem cells
ORGANISM(S): Homo Sapiens 
2023-12-28 | PXD048153 |
ProteomicsSerum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | MassIVE
ProteomicsBRAF inhibitors enhance erythropoiesis and treat anemia through paradoxical activation of MAPK
Erythropoiesis is a crucial part in hematopoietic system, while facing disruptions from various diseases conditions. Anemia and blood shortages has become global challenges, with current finite pharmacological options like EPO or glucocorticoids having limitations, especially in genetic anemias like...
ORGANISM(S): Homo Sapiens 
2024-09-09 | PXD055730 |
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