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MetabolomicsCD73 inhibitor AB680 suppresses glioblastoma in mice by inhibiting purine metabolism and promoting P2RY12<sup>+</sup> microglia transformation.
CD73 (ecto-5'-nucleotidase) is a metabolic immune checkpoint that dephosphorylates AMP to produce adenosine. Adenosine plays a pivotal role in immunosuppressive tumor microenvironment (TME) through adenosine receptors expressed on various immune cells. AB680, a specific CD73 inhibitor, is currently ...
2025-08-04 | MTBLS11084 | MetaboLights
UnknownChinese Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (5A) Registry protocol: rationale, design and methodology.
Not available
S-EPMC10882838 | biostudies-literature
UnknownEarly Death and Survival of Patients With Acute Promyelocytic Leukemia in ATRA Plus Arsenic Era: A Population-Based Study.
Not available
S-EPMC8637823 | biostudies-literature
TranscriptomicsMAQC
The MicroArray Quality Control (MAQC) project was initiated to address these concerns, as well as other performance and analysis issues. We demonstrate the consistency of results within a platform across test sites as well as the high level of cross-platform concordance in terms of genes identified ...
ORGANISM(S): Homo sapiens 
2006-12-04 | E-TABM-132 | biostudies-arrayexpress
UnknownManagement of severe sepsis in patients admitted to Asian intensive care units: prospective cohort study.
Not available
S-EPMC3113333 | biostudies-literature
UnknownThe MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements.
Not available
S-EPMC3272078 | biostudies-literature
UnknownA longitudinal resource for population neuroscience of school-age children and adolescents in China.
Not available
S-EPMC10442366 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
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