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UnknownDeglycosylated Azithromycin Targets Transgelin to Enhance Intestinal Smooth Muscle Function.
Not available
S-EPMC7479357 | biostudies-literature
Proteomics[HPP-2.0] Integrated and high-throughput approach for sensitive analysis of tyrosine phosphoproteome
In this study, we developed a 96-well microplate-based approach to integrate all the sample preparation steps starting from cell culture to MS-compatible pTyr peptide enrichment in three consecutive 96-well microplates. By assembling engineered SH2 domain onto microplate, non-specific adsorption of ...
ORGANISM(S): Homo Sapiens 
2024-02-03 | PXD049140 |
ProteomicsStructure-guided development of chemically tailored peptide binders of RNF43/ZNRF3 to enable versatile design of membrane protein-targeting PROTACs
Targeted membrane protein degradation using cell surface E3 ligases RNF43/ZNRF3 via proteolysis targeting chimeras (PROTACs) represents an effective strategy for treating membrane drug targets that cannot be fully inhibited using traditional inhibitors. Several ingenious chimeras have been developed...
ORGANISM(S): Homo Sapiens 
2025-03-04 | PXD061425 |
ProteomicsProteomic profiles of giant panda spermatozoa seminal plasma
proteomic differences of seminal plasma proteins between healthy and cryptorchidism and normal testis of giant pandas
ORGANISM(S): Ailuropoda Melanoleuca 
2024-03-28 | PXD051040 |
ProteomicsDeKinomics pulse-chases kinase functions in living cells
Cellular context is crucial for understanding the complex and dynamic kinase functions in health and disease. Systematic dissection of kinase-mediated cellular processes requires rapid and precise stimulation (“pulse”) of a kinase of interest, as well as global and in-depth characterization (“chase”...
ORGANISM(S): Homo Sapiens 
2023-10-07 | PXD039316 |
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