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MetabolomicsNMR-based metabonomics and correlative analysis reveals potential bomarkers associated with chronic atrophic gastritis
Chronic atrophic gastritis (CAG) is one of the most important pre-cancerous states with a high prevalence. Exploring of the underlying mechanism and potential biomarkers is of significant importance for CAG. In the present work, 1H NMR-based metabonomics with correlative analysis was performed to an...
2016-08-31 | MTBLS340 | MetaboLights
MetabolomicsKidney Tissue Targeted Metabolic Profiling of Unilateral Ureteral Obstruction Rats by NMR
Renal interstitial fibrosis is a common pathological process in the progression of kidney disease. A nuclear magnetic resonance (NMR) based metabolomics approach was used to analyze the kidney tissues of renal interstitial fibrosis (RIF) rats, induced by unilateral ureteral obstruction (UUO). The co...
2017-10-09 | MTBLS361 | MetaboLights
ProteomicsSpatio-temporal analysis deciphers the energy metabolism disorders in depression based on stable isotope-resolved metabolomics
The severe harm of depression on human life has attracted great attention. However, due to its unclear and extremely complex pathogenesis, the efficacy of existing marketed antidepressants is far from satisfactory. Consequently, it is urgent to understand the pathogenesis of depression from novel pe...
ORGANISM(S): Rattus Rattus 
PXD066143 |
ProteomicsMesenchymal stem cell derived exosomal microRNA-34c-5p ameliorates renal pericyte activation by inhibiting core fucosylation
Renal interstitial fibrosis(RIF) is an incurable pathological lesion in progressive chronic kidney diseases. Myofibroblasts proliferation and microvascular damage are two important events of RIF and pericyte is one of the major sources of myofibroblasts in kidney. However, the underlying mechanisms ...
ORGANISM(S): Mus Musculus 
2020-11-04 | PXD022358 |
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