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TranscriptomicsTranscriptome sequencing of and microarray development for a Helicoverpa zea cell line to investigate in vitro insect cell-baculovirus interactions
The Helicoverpa armigera single-capsid nucleopolyhedrovirus (HaSNPV) can be propagated using H. zea insect cell cultures, for use as a biopesticide against Heliothine agricultural pests.This study sequenced, assembled and functionally annotated 29,586 transcript sequences from cultured H. zea cells ...
ORGANISM(S): Helicoverpa zea 
2012-03-01 | E-GEOD-34418 | biostudies-arrayexpress
TranscriptomicsDetection of microRNA expression during 3T3-L1 pre-adipocyte differentiation using a custom made microarray chip.
Differentiation of 3T3-L1 cells into adipocytes involves a highly orchestrated series of events including clonal expansion, growth arrest and terminal differentiation. The mechanisms coordinating these different steps are not yet fully understood. Here we investigated whether micro (mi)RNAs play a...
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-16229 | biostudies-arrayexpress
GenomicsWhole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma
Cholangiocarcinoma (CCA) is a hepatobiliary malignancy exhibiting high incidence in countries with endemic liver-fluke infection. We analyzed 489 CCAs from 10 countries, combining whole-genome (71 cases), targeted/exome, copy-number, gene expression, and DNA methylation information. Integrative clus...
EGAS00001001653 | EGA
Genomicsena-DATASET-DUKE-NUS-01-04-2016-09:56:06:868-175 - samples
CCA targeted sequencing
EGAD00001001994 | EGA
Genomicsena-DATASET-DUKE-NUS-28-03-2016-04:29:04:072-192 - samples
Cholangiocarcinoma whole genome sequencing data
EGAD00001001988 | EGA
Genomicsena-DATASET-DUKE-NUS-05-12-2017-07:28:25:856-358 - samples
This dataset contains whole genome sequencing FASTQ data for 12 cholangiocarcinoma tumor samples, and their matched normal samples. These 12 samples are in addition to 59 samples available in dataset EGAD00001001988, and consist of patients from Thailand, Romania, and Singapore. Paired-end sequencin...
EGAD00001003834 | EGA
TranscriptomicsLimiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner
Cellular lipid requirements are achieved through a combination of biosynthesis and import programs. Using isotope tracer analysis, we show that type I interferon (IFN) signaling rapidly shifts the balance of these programs by decreasing synthesis and increasing import of cholesterol and long chain f...
ORGANISM(S): Homo sapiens 
2015-12-10 | E-GEOD-73942 | biostudies-arrayexpress
UnknownCanadian Surgery Forum.
Not available
S-EPMC3432251 | biostudies-literature
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