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TranscriptomicsCharacteristic bimodal profiles of RNA polymerase II at thousands of active mammalian promoters
Here, we present PolII binding profiles from high-coverage ChIP-seq on promoters of actively transcribed genes in mouse and humans. We show that the enrichment of PolII near transcription start sites exhibits a stereotypical bimodal structure, with one peak near active transcription start sites and ...
ORGANISM(S): Mus musculus 
2014-06-13 | E-GEOD-58443 | biostudies-arrayexpress
ProteomicsLoss of function variants in SAXO6, encoding a microtubule inner protein of photoreceptor cilia, causes a late-onset retinal dystrophy
Over 500 genes have been linked to various forms of inherited retinal diseases (IRDs), a class of Mendelian conditions affecting the survival and function of rod and cone photoreceptors and leading in most instances to progressive visual loss. Yet, some patients still lack a clear genetic diagnosis,...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2026-01-28 | MSV000100624 | MassIVE
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