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ProteomicsInvestigation of TOMM6 in brains from Tg2576 mice
The protein TOMM6 (translocase of outer mitochondrial membrane 6) was identified as an interacting protein of phospho-S670-GRK2 (G protein-coupled receptor kinase 2 phosphorylated at serine 670) in brain specimens (frontal cortex and hippocampus) of 12-month-old Tg2576 Alzheimer (AD) model mice. Mit...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-16 | PXD073643 | Pride
Tg2576 mouse brain Mitochondria 
ProteomicsInvestigation of PSMA3 in brains of B6 mice
The PSMA3 (Proteasome subunit alpha type-3) protein was identified by ligand affinity chromatography in brain specimens (frontal cortex and hippocampus) of 6-month-old, non-transgenic B6 mice, as a protein which interacts with CPD57 (4-(4-fluorophenyl)-6-(hydroxymethyl)-2-methyl-pyridine-3-carboxami...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-16 | PXD073574 | Pride
Frontal cortex Psma3 B6 mouse Brain Hippocampus 
ProteomicsInvestigation of TOF patient heart specimens
The protein BBLN with largely unknown function was identified in human right ventricular heart specimens from patients undergoing repair surgery for Tetralogy of Fallot (TOF). Proteins from heart specimens were solubilized and subjected to immuno-affinity enrichment with anti-CAMK2D-specific antibod...
ORGANISM(S): Homo sapiens (Human) 
2023-09-18 | PXD044695 | Pride
Human Heart 
TranscriptomicsExpression data from human embryonic kidney cells (HEK293) cultivated in high and low glucose
Gene expression profiling of human embryonic kidney (HEK293) cells was performed to determine the effect of high and low glucose on gene expression. Microarrays were used to identify distinct classes of genes up-regulated in HEK293 cells during cultivation for 7 days in medium with physiological (lo...
ORGANISM(S): Homo sapiens 
2009-04-08 | E-GEOD-15575 | biostudies-arrayexpress
TranscriptomicsEstablishment of a novel model to assess the function of proteins under in vivo conditions
We established a novel model to assess the function of proteins under in vivo conditions. The model relies on the expansion of HEK293 cells in immunodeficient NOD.Scid mice. To validate the novel model, we performed microarray gene expression profiling of NOD.Scid-expanded HEK293 cells relative to c...
ORGANISM(S): Homo sapiens 
2009-10-26 | E-GEOD-18739 | biostudies-arrayexpress
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