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Wild type or miR-155 deficient b cells from 5 individuals each were stimulated with LPS and IL4 for 24hs and profiled.
ORGANISM(S): Mus musculus 
'Non-coding transcripts originating upstream of the immunoglobulin constant region (I-transcripts) are required to direct activation-induced deaminase to initiate class switching in B cells. Differential regulation of I and I1 transcription in response to interleukin-4 (IL-4), hence class switching...
ORGANISM(S): Mus musculus 
We applied a novel negative selection strategy called genomic array footprinting (GAF) to identify genes required for genetic transformation of the gram-positive bacterium Streptococcus pneumoniae. Genome-wide mariner-transposon mutant libraries in S. pneumoniae strain R6 were challenged by transfor...
ORGANISM(S): Streptococcus pneumoniae R6 
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