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TranscriptomicsAffymetrix U133A array data for 111 pediatric acute myeloid leukemia (AML) samples at diagnosis
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML This study characterizes CNA and LOH, gene expression and gene sequence mutations in a representative cross-section through subtypes of pediatric AML. Keywords...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-14471 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Xba SNP array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-15732 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Nsp SNP Array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-04-13 | E-GEOD-15730 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Sty2 SNP array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-15731 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Hind SNP array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-15714 | biostudies-arrayexpress
TranscriptomicsHigh-Resolution Genomic Profiling of Adult and Pediatric Core-Binding-Factor Acute Myeloid Leukemia Reveals New Recurrent Genomic Alterations
To identify cooperating lesions in core-binding-factor acute myeloid leukemia (CBF-AML), we performed single-nucleotide polymorphism (SNP)-array analysis on 300 diagnostic and 41 relapse adult and pediatric leukemia samples. We identified a mean of 1.28 copy number alterations (CNAs) per case at dia...
ORGANISM(S): Homo sapiens 
2012-02-07 | E-GEOD-32462 | biostudies-arrayexpress
TranscriptomicsTranscriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases [2010]
Transcriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases:  A Report From the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Gen...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-35202 | biostudies-arrayexpress
TranscriptomicsTranscriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases [2007]
Transcriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases:  A Report From the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Gen...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-35201 | biostudies-arrayexpress
GenomicsWhole Genome Sequencing of Pediatric Acute Megakaryoblastic Leukemia

We have performed whole genome sequencing of 4 cases of pediatric acute megakaryoblastic leukemia to identify somatic genetic alterations driving leukemogenesis.

phs000413.v1.p1 | EGA
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