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TranscriptomicsGlobal gene expression analysis of PB-Oct4.2A.cherry iPS-/-, PB-Oct4.2A.cherry (low) iPS-/- and ES cells
We have generated iPS cell lines with constitutive Oct4 expression at ES-cell level or 3 times lower. The aim of the experiment was to compare the global gene expression profile between these two cell lines and also between each of them and wild type ES cells. We have analysed two biological replica...
ORGANISM(S): Mus musculus 
2013-04-30 | E-GEOD-45003 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of PADI4 overexpression and inhibition in mouse embryonic stem cells
The enzymatic activity of PADI4 was investigated by overexpression and chemical inhibition to determine the effects of arginine citrullination on histone displacement, reprogramming efficiency and the maintenance of pluripotent stem cells.
ORGANISM(S): Mus musculus 
2013-11-22 | E-MTAB-1975 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptional profiling of induced reprogramming trajectories
To elucidate the interplay between signal transduction and transcriptional regulation in cellular reprogramming, distinct induction routes from epiblast stem cells to naïve pluripotency were evaluated and compared.
ORGANISM(S): Mus musculus 
2019-08-16 | E-MTAB-7901 | biostudies-arrayexpress
UnknownAn alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions.
Not available
S-SCDT-10_15252-EMBJ_2023114221 | biostudies-other
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