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TranscriptomicsImpact of Glucocorticoids and PI3K Inhibition on Gene Expression in Myeloma
We previously noted that combination glucocorticoids and PI3K inhibition induces synergistic cell death. To identify genes involved in myeloma cell death we examined mRNA expression in each individual treatment and in the combination. The glucocoriticoid resistant cells (MM.1RL) are used as a nega...
ORGANISM(S): Homo sapiens 
2015-12-07 | E-GEOD-64704 | biostudies-arrayexpress
TranscriptomicsEffects of SPOP on gene expression in prostate cancer
SPOP is a ubiquitin ligase adaptor frequently mutated in prostate cancer. It is involved in ubiquitination and degradation of substrate proteins. We examined the impact of wild-type and mutant SPOP on the transcriptional profile of prostate cancer cells. We cloned several naturally occurring (in hum...
ORGANISM(S): Homo sapiens 
2014-10-10 | E-GEOD-59432 | biostudies-arrayexpress
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