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ProteomicsDependency of NELF-E-KAT2B epigenetic axis in breast cancer carcinogenesis
Cancer cells undergo transcriptional reprogramming to drive tumor progression and metastasis. Here, we identified the transcriptional complex, NELF (Negative elongation factor), as an important regulator of this process. Using cancer cell lines and patient-derived tumor organoids, we demonstrated th...
ORGANISM(S): Homo Sapiens (human) 
2023-01-28 | PXD031304 | JPOST Repository
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
ProteomicsPhosphoproteomic profiling of WNTinib
Phosphoproteome profiling small molecule on sensitive and insensitive murineHCC tumour organoids
ORGANISM(S): Mus Musculus (mouse) 
2023-03-16 | PXD024958 | JPOST Repository
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